CAS 138775-22-1

fmoc-N-methyl-L-isoleucine

Description:

Fmoc-N-methyl-L-isoleucine is a derivative of the amino acid isoleucine, characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group on the amino group and a methyl group on the nitrogen atom. This compound is commonly used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), due to its ability to protect the amino group during the coupling process while allowing for selective deprotection. The Fmoc group is stable under basic conditions and can be removed under mild acidic conditions, making it a versatile choice for synthesizing peptides with complex sequences. Fmoc-N-methyl-L-isoleucine retains the hydrophobic characteristics of isoleucine, contributing to the overall hydrophobicity of peptides in which it is incorporated. Its structure includes a branched aliphatic side chain, which can influence the conformation and stability of peptides. The compound is typically handled in a laboratory setting, requiring standard safety precautions due to its chemical properties.

Formula: C₂₂H₂₅NO₄

InChI: InChI=1/C22H25NO4/c1-4-14(2)20(21(24)25)23(3)22(26)27-13-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,14,19-20H,4,13H2,1-3H3,(H,24,25)/t14-,20-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=O)O)N(C)C(=O)OCC1c2ccccc2c2ccccc12

Synonyms:

• Fmoc-N-Me-Ile-OH
• N-alpha-(9-fluorenylmethyloxycarbonyl)-N-alpha-Methyl-L-isoleucine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-isoleucine

N-Fmoc-N-methyl-L-isoleucine, 95%

CAS: 138775-22-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₂H₂₅NO₄

Purity: 95%

Molecular weight: 367.45

Ref: 02-H63640

Fmoc-N-Me-Ile-OH

CAS: 138775-22-1

MeIle derivative used in the Fmoc-SPPS of cyclosporin and compstatin analogs.

Formula: C₂₂H₂₅NO₄

Purity: 98.5%

Color and Shape: White Powder

Molecular weight: 367.44

Ref: 01-4042030

L-Isoleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-

CAS: 138775-22-1

Formula: C₂₂H₂₅NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 367.4382

Ref: IN-DA0019JU

Fmoc-N-Me-Ile-OH

CAS: 138775-22-1

Fmoc-N-Me-Ile-OH is a used in peptide synthesis.

Formula: C₂₂H₂₅NO₄

Color and Shape: White Powder

Molecular weight: 367.44

Ref: TM-T19324

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-isoleucine

CAS: 138775-22-1

Formula: C₂₂H₂₅NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 367.45

Ref: 3B-F1129

Fmoc-N-Me-lle-OH

CAS: 138775-22-1

M03363 - Fmoc-N-Me-lle-OH

Formula: C₂₂H₂₅NO₄

Purity: >98%

Color and Shape: Solid, Beige powder

Molecular weight: 367.44500732421875

Ref: 10-M03363

Fmoc-N-Me-Ile-OH

CAS: 138775-22-1

Formula: C₂₂H₂₅NO₄

Molecular weight: 367.44

Ref: 7W-GM4616

Fmoc-N-Me-L-Ile-OH

CAS: 138775-22-1

Fmoc-N-Me-L-Ile-OH

Purity: 98%

Color and Shape: Beige Powder

Molecular weight: 367.44g/mol

Ref: 54-OR52601

Fmoc-N-methyl-L-isoleucine

CAS: 138775-22-1

Fmoc-N-methyl-L-isoleucine is a high quality reagent that is used as an intermediate for the synthesis of complex compounds. It is a useful building block for the synthesis of speciality chemicals and research chemicals. Fmoc-N-methyl-L-isoleucine is also a versatile building block that can be used in reactions involving nucleophilic substitution, reductive amination, Mannich reaction, and hydrogenation. This chemical has been shown to have antihypoxic effects on neurons in vitro.

Formula: C₂₂H₂₅NO₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 367.44 g/mol

Ref: 3D-FF47460