CAS 138797-71-4

fmoc-O-tert-butyl-D-threonine

Description:

Fmoc-O-tert-butyl-D-threonine is a protected amino acid commonly used in peptide synthesis. It features a phenylmethoxycarbonyl (Fmoc) group, which serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The tert-butyl group provides steric hindrance, protecting the hydroxyl group of the threonine side chain, which is crucial for maintaining the integrity of the amino acid during synthesis. This compound is characterized by its stability under standard laboratory conditions, making it suitable for various coupling reactions. Its structure includes a chiral center, which contributes to its specificity in biological applications. Fmoc-O-tert-butyl-D-threonine is typically utilized in solid-phase peptide synthesis, where the Fmoc group can be easily removed under basic conditions, facilitating the sequential addition of amino acids. The compound is valued for its ability to enhance the solubility of peptides and improve the yield of the desired products. Overall, it is an essential building block in the field of medicinal chemistry and peptide research.

Formula: C₂₃H₂₇NO₅

InChI: InChI=1/C23H27NO5/c1-14(29-23(2,3)4)20(21(25)26)24-22(27)28-13-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,14,19-20H,13H2,1-4H3,(H,24,27)(H,25,26)/t14-,20+/m0/s1

Synonyms:

• Fmoc-D-Thr(tBu)-OH
• Fmoc-D-Thr(But)-OH
• O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-threonine
• Fmoc-O-tert.butyl-D-threonine

Fmoc-D-Thr(tBu)-OH

CAS: 138797-71-4

Bachem ID: 4004993.

Formula: C₂₃H₂₇NO₅

Purity: 99.8%

Color and Shape: White

Molecular weight: 397.47

Ref: 01-4004993

D-Threonine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

CAS: 138797-71-4

Formula: C₂₃H₂₇NO₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 397.4642

Ref: IN-DA0019KV

Fmoc-D-Thr(tBu)-OH

CAS: 138797-71-4

Molecular weight: 397.46

Ref: 7W-GM7232

Fmoc-O-Tert-Butyl-D-Threonine

CAS: 138797-71-4

Fmoc-O-Tert-Butyl-D-Threonine

Purity: 98%

Molecular weight: 397.46g/mol

Ref: 54-OR1013385

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-tert-butyl-D-threonine

CAS: 138797-71-4

Formula: C₂₃H₂₇NO₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 397.47

Ref: 3B-F1128

Threonine Impurity 1 (Fmoc-D-Thr(tBu)-OH)

CAS: 138797-71-4

Formula: C₂₃H₂₇NO₅

Molecular weight: 397.47

Ref: 4Z-T-241006

Fmoc-O-tert-butyl-D-threonine

CAS: 138797-71-4

Fmoc-O-tert-butyl-D-threonine is an ion pair that is synthesized using an asymmetric synthesis process. The molecule has been shown to have antiproliferative effects in animals and humans and can inhibit neutrophil function. This synthetic compound has a glycan (a carbohydrate) attached to the side chain, which may be important for its biological activity. Fmoc-O-tert-butyl-D-threonine was synthesized on a solid phase and functional groups were introduced as part of the synthesis process. This molecule also has an inhibitory effect on ulceration in animals.

Formula: C₂₃H₂₇NO₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 397.46 g/mol

Ref: 3D-FF47370

Fmoc-D-Thr(tBu)-OH

CAS: 138797-71-4

M03393 - Fmoc-D-Thr(tBu)-OH

Formula: C₂₃H₂₇NO₅

Purity: 97%

Color and Shape: Light yellow powder

Molecular weight: 397.471

Ref: 10-M03393

FMOC-O-Tert-Butyl-D-Threonine (FMOC-D-Thr(tBu)-OH) extrapure, 98%

CAS: 138797-71-4

Formula: C₂₃H₂₇NO₅

Purity: min. 98%

Color and Shape: White, Crystalline powder, Clear, Colourless

Molecular weight: 397.46

Ref: SR-38217

N-Fmoc-D-Thr(OtBu)-4-13C-4,4,4-d3-OH

Controlled Product

CAS: 138797-71-4

Formula: C₂₂CH₂₄D₃NO₅

Color and Shape: Neat

Molecular weight: 401.48

Ref: TR-F679632

N-Fmoc-D-Thr(OtBu)-4,4,4-d3-OH

Controlled Product

CAS: 138797-71-4

Formula: C₂₃H₂₄D₃NO₅

Color and Shape: Neat

Molecular weight: 400.48

Ref: TR-F679633

Fmoc-D-Thr(tBu)-OH

CAS: 138797-71-4

Formula: C₂₃H₂₇NO₅

Molecular weight: 397.47

Ref: ST-EA-CP-T81014