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CAS 138844-81-2

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Ibandronate sodium

Description:
Ibandronate sodium is a bisphosphonate compound primarily used in the treatment and prevention of osteoporosis, particularly in postmenopausal women. It functions by inhibiting osteoclast-mediated bone resorption, thereby increasing bone mineral density and reducing the risk of fractures. The substance is characterized by its high affinity for hydroxyapatite, which allows it to bind effectively to bone tissue. Ibandronate sodium is typically administered orally or intravenously, with its pharmacokinetics influenced by factors such as food intake and renal function. The compound is known for its relatively long half-life in bone, allowing for less frequent dosing compared to some other bisphosphonates. Common side effects may include gastrointestinal disturbances, musculoskeletal pain, and, in rare cases, osteonecrosis of the jaw. Due to its mechanism of action, Ibandronate sodium is also being investigated for potential applications in other conditions involving bone metabolism. As with any medication, it is essential to consider contraindications and interactions with other drugs when prescribing or using this compound.
Formula:C9H23NO7P2·Na
InChI:InChI=1S/C9H23NO7P2.Na/c1-3-4-5-7-10(2)8-6-9(11,18(12,13)14)19(15,16)17;/h11H,3-8H2,1-2H3,(H2,12,13,14)(H2,15,16,17);
InChI key:InChIKey=WQVSHLXLXKMYEW-UHFFFAOYSA-N
SMILES:C(CCN(CCCCC)C)(P(=O)(O)O)(P(=O)(O)O)O.[Na]
Synonyms:
  • (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
  • BM 21.0955Na
  • Bm 21.0955
  • Bondronat
  • Bondronat, (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid sodium
  • Bondronate
  • Boniva
  • Bonviva
  • Ibandronate sodium
  • Phosphonic acid, P,P′-[1-hydroxy-3-(methylpentylamino)propylidene]bis-, sodium salt (1:1)
  • See more synonyms
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