CAS 1388803-90-4

Vodobatinib

Description:

Vodobatinib, with the CAS number 1388803-90-4, is a small molecule inhibitor primarily targeting the tyrosine kinase activity of certain proteins involved in cellular signaling pathways. It is particularly noted for its potential application in the treatment of various cancers, including those driven by mutations in the BCR-ABL gene, which is commonly associated with chronic myeloid leukemia (CML). The compound exhibits selectivity for specific kinases, which helps to minimize off-target effects and enhance therapeutic efficacy. Vodobatinib's mechanism of action involves the inhibition of ATP binding to the kinase domain, thereby disrupting downstream signaling that promotes tumor growth and survival. In terms of its physical and chemical properties, Vodobatinib is characterized by its molecular structure, which includes specific functional groups that contribute to its biological activity and solubility. Ongoing research and clinical trials continue to evaluate its safety, efficacy, and potential side effects in various patient populations.

Formula: C₂₇H₂₀ClN₃O₂

Synonyms:

• Benzoic acid, 2-chloro-6-methyl-, 2-[4-methyl-3-[2-(3-quinolinyl)ethynyl]benzoyl]hydrazide
• Vodobatinib
• 2-Chloro-6-methyl-N'-(4-methyl-3-(quinolin-3-ylethynyl)benzoyl)benzohydrazide
• N'-(2-chloro-6-methylbenzoyl)-4-methyl-3-[2-(3-quinolyl)ethynyl]-benzohydrazide

Vodobatinib

CAS: 1388803-90-4

Formula: C₂₇H₂₀ClN₃O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 453.9196

Ref: IN-DA01V4NC

Vodobatinib

CAS: 1388803-90-4

Vodobatinib

Purity: ≥98%

Molecular weight: 453.92g/mol

Ref: 54-BUP08225

Vodobatinib

CAS: 1388803-90-4

Vodobatinib (K-0706) is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.

Formula: C₂₇H₂₀ClN₃O₂

Purity: 99.06% - 99.55%

Color and Shape: Solid

Molecular weight: 453.92

Ref: TM-T8882

Vodobatinib

CAS: 1388803-90-4

Vodobatinib is a small molecule that inhibits the phosphorylation of tyrosine kinases and blocks the downstream cellular signaling pathways. It has been used in research to study protein interactions, activator, and ligand. Vodobatinib is also used as a reagent for antibody production. The compound has high purity and is suitable for use in life science studies.

Formula: C₂₇H₂₀ClN₃O₂

Purity: Min. 95%

Molecular weight: 453.9 g/mol

Ref: 3D-NFC80390