CAS 138890-62-7: Brinzolamide

Description:Brinzolamide is a carbonic anhydrase inhibitor primarily used in the treatment of elevated intraocular pressure in conditions such as glaucoma and ocular hypertension. It is a sulfonamide derivative, characterized by its ability to inhibit the enzyme carbonic anhydrase, which plays a crucial role in the production of aqueous humor in the eye. This inhibition leads to a decrease in fluid production, thereby lowering intraocular pressure. Brinzolamide is typically administered as an ophthalmic suspension, and its formulation often includes stabilizers and preservatives to enhance its efficacy and shelf life. The compound is known for its relatively low systemic absorption when applied topically, which minimizes potential side effects. In terms of solubility, brinzolamide is more soluble in organic solvents than in water, which influences its formulation and delivery methods. Overall, brinzolamide is an important therapeutic agent in ophthalmology, providing a non-invasive option for managing intraocular pressure.

Formula:C₁₂H₂₁N₃O₅S₃

InChI:InChI=1S/C12H21N3O5S3/c1-3-14-10-8-15(5-4-6-20-2)23(18,19)12-9(10)7-11(21-12)22(13,16)17/h7,10,14H,3-6,8H2,1-2H3,(H2,13,16,17)/t10-/m0/s1

InChI key:InChIKey=HCRKCZRJWPKOAR-JTQLQIEISA-N

SMILES:O=S(=O)(N)C=1SC2=C(C1)C(NCC)CN(CCCOC)S2(=O)=O

Synonyms:
(4R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide
(4R)-4-(ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
(5R)-5-Ethylamino-3-(3-methoxypropyl)-2,2-dioxo-2λ<sup>6</sup>,9-dithia-3-azabicyclo[4.3.0]nona-7,10-diene-8-sulfonamide
(R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (4R)-
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (R)-
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (S)-
Al 4862
Birnzolamide
See more synonyms
Brinlolamide
(5R)-5-Ethylamino-3-(3-methoxypropyl)-2,2-dioxo-2λ6,9-dithia-3-azabicyclo[4.3.0]nona-7,10-diene-8-sulfonamide
Brinzolamide

Found 14 products.

Product data	Purity	Price range	Estimated delivery
Brinzolamide REF: 3B-B4258CAS: 138890-62-7	>98.0%(HPLC)	40.00 €~104.00 €	Wed 09 Apr 25
Brinzolamide REF: 45-1076363CAS: 138890-62-7	- - -	463.00 €	Tue 15 Apr 25
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (4R)- REF: IN-DA0019S5CAS: 138890-62-7	98%	29.00 €~511.00 €	Wed 16 Apr 25
Brinzolamide REF: TM-T0142CAS: 138890-62-7	100% - 99.84%	34.00 €~259.00 €	Wed 16 Apr 25
Brinzolamide REF: 54-OR1024589CAS: 138890-62-7	99%	54.00 €~1,459.00 €	Thu 17 Apr 25
Brinzolamide REF: 4Z-B-201CAS: 138890-62-7	- - -	To inquire	Thu 17 Apr 25
Brinzolamide REF: 54-BUP11935CAS: 138890-62-7	99.9%	98.00 €~512.00 €	Thu 17 Apr 25
Brinzolamide REF: 86-MM1300.00CAS: 138890-62-7	- - -	821.00 €	Mon 21 Apr 25
Brinzolamide REF: 7W-GP5583CAS: 138890-62-7	- - -	169.00 €~502.00 €	Wed 23 Apr 25
Brinzolamide Impurity 9 REF: 4Z-B-2019CAS: 138890-62-7	- - -	To inquire	Wed 23 Apr 25
BRINZOLAMIDE REF: 10-F387702CAS: 138890-62-7	99.0%	To inquire	Mon 28 Apr 25
Brinzolamide REF: TR-B677601CAS: 138890-62-7	- - -	196.00 €~432.00 €	Mon 28 Apr 25
Brinzolamide REF: 3D-FB29475CAS: 138890-62-7	Min. 98 Area-%	145.00 €~531.00 €	Tue 29 Apr 25
Brinzolamide - Bio-X ™ REF: 3D-BB164262CAS: 138890-62-7	Min. 95%	147.00 €	Tue 29 Apr 25