CAS 138964-58-6

Benzoic acid, 5-chloro-2-[(phenylsulfonyl)amino]-

Description:

Benzoic acid, 5-chloro-2-[(phenylsulfonyl)amino]- is an organic compound characterized by its benzoic acid structure, which includes a carboxylic acid functional group (-COOH) attached to a benzene ring. The presence of a chlorine atom at the 5-position and a phenylsulfonylamino group at the 2-position contributes to its unique chemical properties. This compound is likely to exhibit moderate solubility in polar solvents due to the carboxylic acid group, while the sulfonamide moiety may enhance its reactivity and potential biological activity. The chlorine substituent can influence the compound's electronic properties and steric hindrance, affecting its interactions in chemical reactions. Additionally, the sulfonamide group may impart specific pharmacological properties, making it of interest in medicinal chemistry. Overall, this compound's structure suggests potential applications in pharmaceuticals or agrochemicals, although specific biological activities would require further investigation.

Formula: C₁₃H₁₀ClNO₄S

2-Benzenesulfonamido-5-chlorobenzoic acid

CAS: 138964-58-6

2-Benzenesulfonamido-5-chlorobenzoic acid is a potent inhibitor of the enzyme protein tyrosine phosphatase 1B (PTP1B). PTP1B is a negative regulator of insulin signaling and has been found to be associated with type 2 diabetes. This drug binds to the active site of PTP1B and prevents it from dephosphorylating tyrosine residues on the insulin receptor, which activates downstream signaling pathways that lead to glucose uptake. 2-Benzenesulfonamido-5-chlorobenzoic acid has been shown to inhibit tumor cell proliferation in vitro and in vivo. It also inhibits tumor angiogenesis by blocking vascular endothelial growth factor receptor 2 (VEGFR2) signaling.

Formula: C₁₃H₁₀ClNO₄S

Purity: Min. 95%

Molecular weight: 311.74 g/mol

Ref: 3D-NFA96458