CAS 13898-60-7

Benzo[g]quinazoline-2,4(1H,3H)-dione

Description:

Benzo[g]quinazoline-2,4(1H,3H)-dione, with the CAS number 13898-60-7, is a heterocyclic organic compound characterized by its fused ring structure, which includes a quinazoline core. This compound features two carbonyl groups (C=O) at the 2 and 4 positions, contributing to its diketone classification. It is typically a crystalline solid and exhibits properties such as moderate solubility in organic solvents. The presence of the quinazoline moiety suggests potential biological activity, as many derivatives of quinazoline are known for their pharmacological properties, including anticancer and antimicrobial activities. The compound may also participate in various chemical reactions, such as nucleophilic additions or cycloadditions, due to the electrophilic nature of the carbonyl groups. Its unique structure and reactivity make it of interest in medicinal chemistry and materials science. Safety data should be consulted for handling, as with all chemical substances, to ensure proper precautions are taken during use.

Formula: C₁₂H₈N₂O₂

InChI: InChI=1S/C12H8N2O2/c15-11-9-5-7-3-1-2-4-8(7)6-10(9)13-12(16)14-11/h1-6H,(H2,13,14,15,16)

InChI key: InChIKey=TUYHDHWBWUTAQM-UHFFFAOYSA-N

SMILES: O=C1C=2C(=CC3=C(C2)C=CC=C3)NC(=O)N1

Synonyms:

• Benzo[g]quinazoline-2,4-diol
• S 2676
• Benzo[g]quinazoline-2,4(1H,3H)-dione
• 1H,2H,3H,4H-Benzo[g]quinazoline-2,4-dione

1H,2H,3H,4H-Benzo[G]quinazoline-2,4-dione

CAS: 13898-60-7

1H,2H,3H,4H-Benzo[G]quinazoline-2,4-dione is an analog of the purine nucleoside adenine. It has been shown to bind to DNA by interacting with the polymerase and fluorescent probes. In addition to binding to DNA, 1H,2H,3H,4H-Benzo[G]quinazoline-2,4-dione interacts with other dna binding proteins and has been shown to form conformational triplexes with complementary strands of DNA. The compound also binds to ribonucleoprotein and can be used as a fluorescent probe for RNA synthesis. This compound has been shown to have thermal stability as well as denaturation properties that are dependent on pH and ionic strength.

Formula: C₁₂H₈N₂O₂

Purity: Min. 95%

Molecular weight: 212.2 g/mol

Ref: 3D-NAA89860