CAS 138998-91-1

Adenosine, 2'-deoxy-, 5'-[hydrogen[[hydroxy(phosphonooxy)phosphinyl]methyl]phosphonate]

Description:

Adenosine, 2'-deoxy-, 5'-[hydrogen[[hydroxy(phosphonooxy)phosphinyl]methyl]phosphonate], commonly referred to as a modified nucleotide, is characterized by its structural components that include a deoxyribose sugar, an adenine base, and a phosphonate group. This compound features a phosphonate moiety, which is a phosphorus atom bonded to four oxygen atoms, one of which is part of a hydroxyl group. The presence of the phosphonate group imparts unique chemical properties, such as increased stability against hydrolysis compared to traditional phosphate esters. This modification can enhance the compound's bioavailability and potential therapeutic applications, particularly in the context of nucleic acid analogs. The compound is typically soluble in polar solvents and may exhibit specific interactions with biological macromolecules, influencing its role in biochemical pathways. Its CAS number, 138998-91-1, allows for precise identification in chemical databases, facilitating research and development in fields such as medicinal chemistry and molecular biology.

Formula: C₁₁H₁₈N₅O₁₁P₃

2'-Deoxyadenosine-5'-[(a,b)-methyleno]triphosphate sodium salt - 10 mM aqueous solution

CAS: 138998-91-1

2'-Deoxyadenosine-5'-[(a,b)-methyleno]triphosphate sodium salt - 10 mM aqueous solution is a molecule that binds to the epidermal growth factor receptor (EGFR). It is a nucleotide that is used in pharmaceutical preparations to treat certain types of cancer. This drug can be used in tissue culture to increase follicular growth and pge2 levels. 2'-Deoxyadenosine-5'-[(a,b)-methyleno]triphosphate sodium salt - 10 mM aqueous solution has been shown to inhibit the proliferation of monoclonal antibody-producing cells by inhibiting DNA synthesis through the inhibition of RNA polymerase II and polymerase chain reaction.

Formula: C₁₁H₁₈N₅O₁₁P₃·xNa

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 489.21 g/mol

Ref: 3D-ND46688