CAS 1392-21-8: kitasamycin
Description:Kitasamycin is a macrolide antibiotic that is primarily produced by the fermentation of certain strains of Streptomyces bacteria. It is characterized by its large lactone ring structure, which is typical of macrolides, and contains multiple sugar moieties that contribute to its biological activity. Kitasamycin exhibits antibacterial properties, particularly against Gram-positive bacteria and some Gram-negative bacteria, making it useful in treating various infections. Its mechanism of action involves inhibiting bacterial protein synthesis by binding to the 50S ribosomal subunit. Additionally, kitasamycin has shown some antifungal activity and is sometimes used in veterinary medicine. The compound is relatively stable under acidic conditions but may be sensitive to hydrolysis in alkaline environments. Its solubility varies depending on the solvent, and it is typically administered in a form that maximizes its bioavailability. Overall, kitasamycin is an important compound in the field of antibiotics, contributing to the treatment of bacterial infections and expanding the arsenal of antimicrobial agents.
Formula:C41H69NO13
InChI:InChI=1/C41H69NO13/c1-23(2)19-31(46)53-39-27(6)51-33(22-41(39,7)8)54-36-26(5)52-40(35(48)34(36)42(9)10)55-37-28(17-18-43)20-24(3)29(44)16-14-12-13-15-25(4)50-32(47)21-30(45)38(37)49-11/h12-14,16,18,23-30,33-40,44-45,48H,15,17,19-22H2,1-11H3/b13-12+,16-14+/t24-,25-,26?,27?,28?,29?,30-,33?,34?,35?,36?,37+,38+,39?,40?/m1/s1
- Synonyms:
- Acetyl Kitasamycin
- Ayermicina
- C 637
- C637
- Formacidine
- Kitasamycin Base
- Leucomycin
- Leucomycin Base
- Leucomycin Hydrate
- Selectomycin
- See more synonyms
- Sineptina
- Stereomycine
- Syneptine
- [(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl]acetaldehyde (non-preferred name)
