CAS 139225-22-2

Panamesine

Description:

Panamesine, identified by its CAS number 139225-22-2, is a chemical compound that belongs to the class of substances known as antihistamines. It is primarily characterized by its ability to antagonize histamine receptors, which makes it useful in alleviating allergic reactions and symptoms associated with conditions such as hay fever and urticaria. The compound exhibits a specific affinity for H1 receptors, contributing to its effectiveness in reducing allergic responses. Additionally, Panamesine may possess sedative properties, a common trait among many first-generation antihistamines, although its sedative effects can vary among individuals. The chemical structure of Panamesine includes functional groups that enhance its pharmacological activity and bioavailability. As with many pharmaceuticals, the safety profile, potential side effects, and interactions with other medications are important considerations in its use. Overall, Panamesine represents a significant option in the management of allergic conditions, reflecting the broader category of antihistamines in therapeutic applications.

Formula: C₂₃H₂₆N₂O₆

InChI: InChI=1S/C23H26N2O6/c1-28-18-5-3-17(4-6-18)25-14-19(31-22(25)26)13-24-10-8-23(27,9-11-24)16-2-7-20-21(12-16)30-15-29-20/h2-7,12,19,27H,8-11,13-15H2,1H3/t19-/m0/s1

InChI key: InChIKey=NINYZUDVKTUKIA-IBGZPJMESA-N

SMILES: OC1(C=2C=C3C(=CC2)OCO3)CCN(C[C@H]4CN(C(=O)O4)C5=CC=C(OC)C=C5)CC1

Synonyms:

• 2-Oxazolidinone, 5-[[4-(1,3-benzodioxol-5-yl)-4-hydroxy-1-piperidinyl]methyl]-3-(4-methoxyphenyl)-, (S)-
• Panamesine
• (5S)-5-[[4-(1,3-Benzodioxol-5-yl)-4-hydroxy-1-piperidinyl]methyl]-3-(4-methoxyphenyl)-2-oxazolidinone
• 2-Oxazolidinone, 5-[[4-(1,3-benzodioxol-5-yl)-4-hydroxy-1-piperidinyl]methyl]-3-(4-methoxyphenyl)-, (5S)-

2-Oxazolidinone, 5-[[4-(1,3-benzodioxol-5-yl)-4-hydroxy-1-piperidinyl]methyl]-3-(4-methoxyphenyl)-, (5S)-

CAS: 139225-22-2

Formula: C₂₃H₂₆N₂O₆

Purity: 99.43%

Color and Shape: Solid

Molecular weight: 426.4623

Ref: IN-DA001AIS

Panamesine

CAS: 139225-22-2

Panamesine is a research tool that belongs to the class of ligands and receptors. It is an activator of ion channels. Panamesine has been shown to bind to the receptor for the neurotransmitter GABA, which is one of the main inhibitory neurotransmitters in the brain. This binding causes a conformational change in the receptor, causing it to be activated and opening up ion channels. The activation of these channels leads to a decrease in neuronal excitability and increased synaptic inhibition.

Formula: C₂₃H₂₆N₂O₆

Purity: Min. 95%

Molecular weight: 426.5 g/mol

Ref: 3D-PFA22522

Panamesine

CAS: 139225-22-2

Panamesine (EMD 57445) is a high affinity receptor ligand for sigma (IC50: 6 nM) with potential for atypical antipsychotic studies.

Formula: C₂₃H₂₆N₂O₆

Color and Shape: Solid

Molecular weight: 426.46

Ref: TM-T62312