CAS 13924-98-6

Methyl 6-oxo-1,6-dihydropyrazine-2-carboxylate

CAS: 13924-98-6

Methyl 6-oxo-1,6-dihydropyrazine-2-carboxylate is a lysine methyltransferase inhibitor. It has been shown to inhibit the DNA methylation and histone lysine methylation of mammalian cells, leading to changes in gene expression. Methyl 6-oxo-1,6-dihydropyrazine-2-carboxylate inhibits the uptake of methionine into cells and prevents its conversion to S-adenosylmethionine (SAM). SAM is an important donor of methyl groups for methylating DNA and histones. Methyl 6-oxo-1,6-dihydropyrazine-2 carboxylate also inhibits actin filament formation by preventing the binding of regulatory effector proteins such as cofilin, which is involved in nucleotide exchange on actin filaments.

Formula: C₆H₆N₂O₃

Purity: Min. 95%

Molecular weight: 154.12 g/mol

Ref: 3D-NAA92498