CAS 1392826-25-3

Deutetrabenazine

Description:

Deutetrabenazine is a chemical compound primarily used as a medication for the treatment of movement disorders, particularly in patients with tardive dyskinesia and Huntington's disease. It is a deuterated form of tetrabenazine, which means that some of its hydrogen atoms are replaced with deuterium, a heavier isotope of hydrogen. This modification enhances its pharmacokinetic properties, leading to a longer half-life and potentially improved efficacy. Deutetrabenazine functions as a vesicular monoamine transporter 2 (VMAT2) inhibitor, which reduces the release of monoamines, particularly dopamine, in the brain. This action helps to alleviate involuntary movements associated with certain neurological conditions. The compound is typically administered orally and is subject to specific dosing regimens based on individual patient needs. Its safety profile includes potential side effects such as sedation, depression, and gastrointestinal disturbances, necessitating careful monitoring during treatment. Overall, deutetrabenazine represents a significant advancement in the management of hyperkinetic movement disorders.

Tetrabenazine-d6 (Deutetrabenazine)

CAS: 1392826-25-3

Formula: C₁₉H₂₁D₆NO₃

Molecular weight: 323.47

Ref: 4Z-T-7863

Tetrabenazine-d6

CAS: 1392826-25-3

Tetrabenazine D6 is the deuterium-labeled Tetrabenazine. Tetrabenazine is a VMAT-inhibitor used for the treatment of hyperkinetic movement disorder.

Formula: C₁₉H₂₇NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 323.46

Ref: TM-T17047

Tetrabenazine-d6

Controlled Product

CAS: 1392826-25-3

Applications Labelled Tetrabenazine. Dopamine depleting agent. An antidyskinetic; antipsychotic.
References Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966), Janovic, J., et al.: Ann. Neurol., 11, 41 (1982), Janovic, J., et al.: Neurology, 38, 391 (1988),

Formula: C₁₉H₂₁D₆NO₃

Color and Shape: Neat

Molecular weight: 323.46

Ref: TR-T284002

Tetrabenazine-d6

Controlled Product

CAS: 1392826-25-3

Tetrabenazine is a drug that is used to treat Parkinson's disease. It decreases the release of dopamine, which can reduce symptoms such as tremors and rigidity. Tetrabenazine has been shown to be an effective treatment for Parkinson's disease in clinical trials with long-term efficacy. Tetrabenazine also has a number of side effects, including hypotension, hallucinations, and depression.br>Tetrabenazine can interact with other drugs or medications such as monoamine oxidase inhibitors, antidepressants, or antipsychotics. This medication should not be taken by people who have liver impairment, because it may lead to liver damage. br>Tetrabenazine is a drug that belongs to the class of pharmacological agents known as selective monoamine reuptake inhibitors (SSRIs). These agents work by blocking the reuptake of serotonin (5-HT), dopamine (DA), or norepinephrine (NE) into the pres

Formula: C₁₉H₂₁D₆NO₃

Purity: Min. 95%

Molecular weight: 323.46 g/mol

Ref: 3D-FT167152