CAS: 1393-48-2 - thiostrepton from streptomyces azureus

Formula: C₇₂H₈₅N₁₉O₁₈S₅

InChI: InChI=1S/C72H85N19O18S5/c1-14-26(3)47-63(105)78-30(7)57(99)75-28(5)56(98)76-31(8)58(100)91-72-19-18-40(66-85-43(22-111-66)59(101)77-29(6)55(97)74-27(4)54(73)96)81-52(72)42-21-112-67(83-42)49(34(11)109-69(107)41-20-37(32(9)92)36-16-17-39(79-47)51(95)50(36)80-41)89-60(102)44-24-113-68(86-44)53(71(13,108)35(12)94)90-62(104)45-23-110-65(84-45)38(15-2)82-64(106)48(33(10)93)88-61(103)46-25-114-70(72)87-46/h15-17,20-22,24-26,30-35,39,45,47-49,51-53,79,92-95,108H,4-6,14,18-19,23H2,1-3,7-13H3,(H2,73,96)(H,74,97)(H,75,99)(H,76,98)(H,77,101)(H,78,105)(H,82,106)(H,88,103)(H,89,102)(H,90,104)(H,91,100)/b38-15-/t26-,30-,31-,32-,33+,34+,35+,39+,45+,47?,48?,49-,51?,52+,53+,71+,72+/m0/s1

InChI key: InChIKey=NSFFHOGKXHRQEW-MRTIMCRRSA-N

SMILES: O=C1OC(C)C2NC(=O)C=3N=C(SC3)C(NC(=O)C4N=C(SC4)C(=CC)NC(=O)C(NC(=O)C=5N=C(SC5)C6(NC(=O)C(NC(=O)C(=C)NC(=O)C(NC(=O)C(NC7C=CC=8C(=NC1=CC8C(O)C)C7O)C(C)CC)C)C)CCC(=NC6C=9N=C2SC9)C%10=NC(=CS%10)C(=O)NC(=C)C(=O)NC(=C)C(=O)N)C(O)C)C(O)(C)C(O)C

Synonyms:

• Alaninamide, <span class="text-smallcaps">L</smallcap>-threonyl-(4S)-2-[(1Z)-1-amino-1-propenyl]-4,5-dihydro-4-thiazolecarbonyl-2-[(1S,2S,3R)-1-amino-2,3-dihydroxy-2-methylbutyl]-4-thiazolecarbonyl-2-[(5R,6S)-6-[2-[(1S,2R)-1-amino-2-hydroxypropyl]-4-thiazolyl]-5-[[N-[(7R,8S)-2-carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-<smallcap>L</smallcap>-isoleucyl-<smallcap>L</smallcap>-alanyl-2,3-didehydroalanyl-<smallcap>L</span>-alanyl]amino]-5-(4-carboxy-2-thiazolyl)-3,4,5,6-tetrahydro-2-pyridinyl]-4-thiazolecarbonyl-2,3-didehydroalanyl-2,3-didehydro-, (1′→4)-lactone, (4→1)-lactam
• Alaninamide, N-[(7R,8S)-2-carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-<span class="text-smallcaps">L</smallcap>-isoleucyl-<smallcap>L</smallcap>-alanyl-2,3-didehydroalanyl-<smallcap>L</span>-alanyl-2-[(4aR,11S,14Z,18S,21S,28S,32aS)-4a-amino-21-[(1S,2R)-1,2-dihydroxy-1-methylpropyl]-14-ethylidene-3,4,4a,9,10,11,12,13,14,18,19,20,21,27,28,32a-hexadecahydro-11,28-bis[(1R)-1-hydroxyethyl]-9,12,19,26-tetraoxo-17H,26H-8,5:18,15:25,22:32,29-tetranitrilo-5H,15H-pyrido[3,2-m][1,11,17,24,4,7,20,27]tetrathiatetraazacyclotriacontin-2-yl]-4-thiazolecarbonyl-2,3-didehydroalanyl-2,3-didehydro-, (1→5²⁸)-lactone
• Bryamycin
• Gargon
• N-{3-[(3-amino-3-oxoprop-1-en-2-yl)amino]-3-oxoprop-1-en-2-yl}-2-[(11E)-37-(butan-2-yl)-18-(2,3-dihydroxybutan-2-yl)-11-ethylidene-59-hydroxy-8,31-bis(1-hydroxyethyl)-26,40,46-trimethyl-43-methylidene-6,9,16,23,28,38,41,44,47-nonaoxo-27-oxa-3,13,20,56-tetrathia-7,10,17,24,36,39,42,45,48,52,58,61,62,63,64-pentadecaazanonacyclo[23.23.9.3~29,35~.1~2,5~.1~12,15~.1~19,22~.1~54,57~.0~1,53~.0~32,60~]tetrahexaconta-2(64),4,12(63),19(62),21,29,31,33,51,54,57,60-dodecaen-51-yl]-1,3-thiazole-4-carboxamide (non-preferred name)
• NSC 170365
• NSC 81722
• Thiactin
• Thiostrepton
• Thiostrepton A

Thiostrepton, Streptomyces laurentii, 90+%

CAS: 1393-48-2

Thiostrepton exhibits antibiotic activity through blockade of ribosome turnover after an elongation step in protein …

• Formula: C₇₂H₈₅O₁₈N₁₉S₅
• Purity: 90+%
• Color and Shape: Powder
• Molecular weight: 1664.89

Thiostrepton

CAS: 1393-48-2

Antibiotics nesoi

• Formula: C₇₂H₈₅N₁₉O₁₈S₅
• Color and Shape: White Powder
• Molecular weight: 1663.49235

Thiostrepton

CAS: 1393-48-2

• Formula: C₆₁H₇₃N₁₅O₁₄S₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 1368.5844

Thiostrepton

CAS: 1393-48-2

• Formula: C₇₂H₈₅O₁₈N₁₉S₅
• Purity: ≥ 98.0%
• Color and Shape: White to pale yellow powder
• Molecular weight: 1664.89

Thiostrepton from Streptomyces azureus

CAS: 1393-48-2

• Formula: C₇₂H₈₅N₁₉O₁₈S₅
• Purity: By hplc: 99.30% (Typical Value in Batch COA)
• Color and Shape: white powder
• Molecular weight: 1,664.89g/mol

Thiostrepton

CAS: 1393-48-2

Thiostrepton (Alaninamide) is a one of the CYCLIC PEPTIDES from Streptomyces that is active against …

• Formula: C₇₂H₈₅N₁₉O₁₈S₅
• Purity: 99.57%
• Color and Shape: Solid
• Molecular weight: 1664.89

Thiostrepton

CAS: 1393-48-2

Stability Hygroscopic Applications Natural antibiotic derived from Streptomyces. References Starosta, A., et al.; Chem. Biol., …

• Formula: C₇₂H₈₅N₁₉O₁₈S₅
• Color and Shape: Neat
• Molecular weight: 1664.89

Thiostrepton

CAS: 1393-48-2

Thiostrepton is a chemical compound that acts as an antibiotic. It binds to the enzyme …

• Formula: C₇₂H₈₅N₁₉O₁₈S₅
• Purity: Min. 95%
• Color and Shape: White To Light (Or Pale) Yellow Solid
• Molecular weight: 1,664.89 g/mol