
CAS 1393813-42-7
:N-[5-(4-bromophenyl)-6-chloro-4-pyrimidinyl]-N'-propyl-Sulfamide
Description:
N-[5-(4-bromophenyl)-6-chloro-4-pyrimidinyl]-N'-propyl-sulfamide is a chemical compound characterized by its unique structural features, which include a pyrimidine ring substituted with a bromophenyl group and a chlorine atom. This compound belongs to the class of sulfamides, which are known for their sulfonamide functional group (-SO2NH2) that contributes to their biological activity. The presence of the bromine and chlorine substituents can influence the compound's reactivity, solubility, and potential pharmacological properties. Typically, such compounds may exhibit antimicrobial or antitumor activities, making them of interest in medicinal chemistry. The propyl group attached to the sulfamide nitrogen can affect the lipophilicity and overall pharmacokinetics of the molecule. As with many synthetic organic compounds, the specific characteristics, including melting point, solubility, and spectral properties, would need to be determined experimentally or sourced from chemical databases for precise applications in research or industry.
Formula:C13H14BrClN4O2S
Synonyms:- N-(5-(4-Bromophenyl)-6-Chloro-4-Pyrimidinyl)-N'-Propylsulfamide
- N-(5-(4-bromophenyl)-6-chloropyrimidin-4-yl)propane-1-sulfamide
- Mecitentan Pyrimidine Amine Impurity
- N-[5-(4-broMophenyl)-6-chloro-4-pyriMidinyl]-N'-propyl-SulfaMide
- N-[5-(4-bromophenyl)-6-chloro-4-pyrimidinyl]-N'-propyl-Sulfa...
- N-[5-(4-Bromphenyl)-6-chlorpyrimidin-4-yl]-N'-propylsulfamid
- Macitentan Impurity 16
- 5-(4-bromophenyl)-6-chloro-N-(propylsulfamoyl)pyrimidin-4-amine
- SulfaMide, N-[5-(4-broMophenyl)-6-chloro-4-pyriMidinyl]-N'-propyl-
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Found 6 products.
SulfaMide, N-[5-(4-broMophenyl)-6-chloro-4-pyriMidinyl]-N'-propyl-
CAS:Formula:C13H14BrClN4O2SPurity:95%Color and Shape:SolidMolecular weight:405.6979N-[5-(4-Bromophenyl)-6-Chloro-4-Pyrimidinyl]-N-Propylsulfamide
CAS:N-[5-(4-Bromophenyl)-6-Chloro-4-Pyrimidinyl]-N-PropylsulfamidePurity:98%Molecular weight:405.70g/molMacitentan Impurity 19
CAS:Formula:C13H14BrClN4O2SColor and Shape:White To Off-White SolidMolecular weight:405.70N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N’-propylsulfamide
CAS:Purity:95%Molecular weight:403.97N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-propylsulfamide
CAS:Controlled Product<p>Applications N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-propylsulfamide is a useful synthetic intermediate in the synthesis of Macitentan (M105005); an orally active, potent dual endothelin receptor antagonist used for pulmonary arterial hypertension.<br>References Bolli, M.H., et al.: J. Med. Chem., 55, 7849 (2012)<br></p>Formula:C13H14BrClN4O2SColor and Shape:NeatMolecular weight:405.7





