CAS 139481-59-7: Candesartan

Description: Candesartan is an angiotensin II receptor antagonist primarily used in the treatment of hypertension and heart failure. It belongs to the class of medications known as sartans, which work by blocking the action of angiotensin II, a hormone that constricts blood vessels and increases blood pressure. The chemical formula of candesartan is C24H20N6O3, and it features a biphenyl structure with a tetrazole ring, contributing to its pharmacological properties. Candesartan is typically administered in oral form and is known for its long half-life, allowing for once-daily dosing. It is well-absorbed in the gastrointestinal tract, although its bioavailability can be affected by food intake. Common side effects may include dizziness, fatigue, and hypotension, while serious adverse effects can involve renal impairment and hyperkalemia. Candesartan is contraindicated in pregnancy due to potential harm to the fetus. Overall, it is an effective medication for managing high blood pressure and improving cardiovascular outcomes in patients with heart failure.

Formula: C₂₄H₂₀N₆O₃

InChI: InChI=1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)

InChI key: InChIKey=HTQMVQVXFRQIKW-UHFFFAOYSA-N

SMILES: O=C(O)C1=CC=CC=2N=C(OCC)N(C21)CC=3C=CC(=CC3)C=4C=CC=CC4C5=NN=NN5

Synonyms:

• (1,1'-biphenyl)-4-yl)methyl)-
• (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• 1-((2′-(1H-Tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid
• 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate
• 1H-Benzimidazole-7-carboxylic acid
• 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
• 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
• 2-Ethoxy-1-([4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl)-1H-1,3-benzodiazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]-7-benzimidazolecarboxylic acid
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazol-7-carboxylic acid
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid
• 2-Ethoxy-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid
• 2-Ethoxy-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]-3H-benzoimidazole-4-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• 2-ethoxy-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid
• 3-[[2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-ethoxy-3H-benzimidazole-4-carboxylic acid
• Blopress
• Blopress (TN)
• C07468
• Candesartan (USAN)
• Candesartan M1
• Candesartan [USAN:INN]
• Chebi:3347
• Cv 11974
• D00522
• imidazole-7-carboxylic acid
• lic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• Candesartan
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-

Candesartan, 98%

CAS: 139481-59-7

Candesartan is a selective AT1 (angiotensin II receptor 1) antagonist. Antagonism of angiotensin receptors inhibits …

• Formula: C₂₄H₂₀N₆O₃
• Purity: 98%
• Color and Shape: Powder, White to pale cream
• Molecular weight: 440.45

Candesartan Cilexetil Related Compound G (1-{[2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl}-2-ethoxybenzimidazole-7-carboxylic acid)

CAS: 139481-59-7

Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

• Formula: C₂₄H₂₀N₆O₃
• Color and Shape: White Powder
• Molecular weight: 440.15969

Candesartan

CAS: 139481-59-7

Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of …

• Formula: C₂₄H₂₀N₆O₃
• Purity: 98.30% - 99.55%
• Color and Shape: Colorless Solid Crystalline
• Molecular weight: 440.47

Candesartan

CAS: 139481-59-7

• Formula: C₂₄H₂₀N₆O₃
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 440.454

Candesartan (Candesartan Cilexetil EP Impurity G, Candesartan Cilexetil USP Related Compound G)

CAS: 139481-59-7

• Formula: C₂₄H₂₀N₆O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 440.46

Candesartan

CAS: 139481-59-7

• Formula: C₂₄H₂₀N₆O₃
• Molecular weight: 440.45

2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid (Candesartan)

CAS: 139481-59-7

• Formula: C₂₄H₂₀N₆O₃
• Color and Shape: Off White
• Molecular weight: 440.45

Candesartan 100 µg/mL in Acetonitrile:Methanol

CAS: 139481-59-7

• Formula: C₂₄H₂₀N₆O₃
• Color and Shape: Single Solution
• Molecular weight: 440.45

Candesartan

CAS: 139481-59-7

• Formula: C₂₄H₂₀N₆O₃
• Color and Shape: Neat
• Molecular weight: 440.45

Candesartan

CAS: 139481-59-7

Impurity Candesartan Cilexetil EP Impurity G Applications Candesartan (Candesartan Cilexetil EP Impurity G) is an …

• Formula: C₂₄H₂₀N₆O₃
• Color and Shape: Off White
• Molecular weight: 440.45

Candesartan - Bio-X ™

CAS: 139481-59-7

Candesartan is a drug that belongs to the class of angiotensin II receptor antagonists and …

• Formula: C₂₄H₂₀N₆O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 440.45 g/mol

Candesartan

CAS: 139481-59-7

Angiotensin II receptor I antagonist; anti-hypertensive

• Formula: C₂₄H₂₀N₆O₃
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 440.46 g/mol