CAS 1394854-52-4

N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine

Description:

N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine, with the CAS number 1394854-52-4, is a chemical compound that exhibits characteristics typical of complex organic molecules. It features a multi-ring structure, incorporating both pyridine and pyrimidine moieties, which contribute to its potential biological activity. The presence of the β-alanine group suggests that it may interact with biological systems, possibly influencing neurotransmitter pathways or acting as a modulator in various biochemical processes. The compound's structural complexity may also indicate potential for diverse interactions with proteins or enzymes. Its solubility, stability, and reactivity would depend on the specific functional groups and the overall molecular conformation. As a compound of interest in medicinal chemistry, it may be investigated for therapeutic applications, particularly in the context of neurological or psychiatric disorders, given the presence of the benzazepine structure, which is often associated with such activities. Further studies would be necessary to elucidate its pharmacological properties and mechanisms of action.

Formula: C₂₂H₂₃N₅O₂

InChI: InChI=1S/C22H23N5O2/c28-21(29)7-11-24-19-14-20(26-22(25-19)18-6-3-10-23-15-18)27-12-8-16-4-1-2-5-17(16)9-13-27/h1-6,10,14-15H,7-9,11-13H2,(H,28,29)(H,24,25,26)

InChI key: InChIKey=LJIFOCRGDDQFJF-UHFFFAOYSA-N

SMILES: N(CCC(O)=O)C1=CC(=NC(=N1)C=2C=CC=NC2)N3CCC=4C(CC3)=CC=CC4

Synonyms:

• N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine
• 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-3-yl)pyrimidin-4-yl)amino)propanoic acid
• β-Alanine, N-[2-(3-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-
• GSK J2

GSK-J2

CAS: 1394854-52-4

Formula: C₂₂H₂₅Cl₂N₅O₂

Purity: 97.55%

Color and Shape: Solid

Molecular weight: 462.3722

Ref: IN-DA009CC6

GSK-J2

CAS: 1394854-52-4

GSK-J2

Formula: C₂₂H₂₃N₅O₂

Purity: ≥95%

Molecular weight: 389.45

Ref: 54-BUP13004

GSK-J2

CAS: 1394854-52-4

GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.

Formula: C₂₂H₂₃N₅O₂

Purity: 98.13%

Color and Shape: Solid

Molecular weight: 389.45

Ref: TM-T11476

GSK J2

CAS: 1394854-52-4

GSK J2 is a substance that inhibits the activity of histone methyltransferase enzymes. This drug has been shown to inhibit tumor growth and induce apoptosis in cancer cells. GSK J2 also increases insulin sensitivity, which may be due to its ability to suppress the production of Th17 cells. GSK J2 has been shown to improve insulin sensitivity in patients with type 2 diabetes. GSK J2 is an inhibitor of Hdac, a class of enzymes that regulate epigenetic gene expression. It has been shown to inhibit the growth factor-induced phosphorylation and activation of Akt/mTORC1 signaling pathway, which leads to decreased cell proliferation and increased apoptosis in mammalian cells.

Formula: C₂₂H₂₃N₅O₂

Purity: Min. 95%

Molecular weight: 389.45 g/mol

Ref: 3D-UFC85452