CAS 1395084-25-9

MS-436

Description:

MS-436, identified by its CAS number 1395084-25-9, is a chemical compound that has garnered attention in various fields, particularly in medicinal chemistry and pharmacology. While specific characteristics such as its molecular structure, physical properties, and biological activity may vary, compounds like MS-436 are typically evaluated for their potential therapeutic applications. They may exhibit properties such as solubility in organic solvents, stability under various conditions, and specific reactivity with biological targets. The compound's efficacy, safety profile, and mechanism of action are crucial for its development as a pharmaceutical agent. Additionally, MS-436 may be subject to regulatory scrutiny, requiring comprehensive studies to assess its pharmacokinetics and toxicity. As research progresses, detailed information regarding its characteristics, including spectroscopic data and biological assays, will become available, contributing to a better understanding of its potential uses in clinical settings.

Formula: C₁₈H₁₇N₅O₃S

Synonyms:

• Ms436
• (E)-4-[2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide
• MS 436

MS436

CAS: 1395084-25-9

MS436

Purity: ≥95%

Molecular weight: 383.42g/mol

Ref: 54-BUP09638

MS436

CAS: 1395084-25-9

MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.

Formula: C₁₈H₁₇N₅O₃S

Purity: 97.95% - 98.92%

Color and Shape: Solid

Molecular weight: 383.42

Ref: TM-T1854

4-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide

Controlled Product

CAS: 1395084-25-9

Formula: C₁₈H₁₇N₅O₃S

Color and Shape: Neat

Molecular weight: 829.513

Ref: TR-A612095

MS436

CAS: 1395084-25-9

MS436 is a synthetic small molecule inhibitor, which is designed through rational drug design and chemical synthesis. It functions by specifically inhibiting bromodomain-containing proteins, particularly targeting the BET (bromodomain and extra-terminal) family proteins. The mode of action involves binding to the acetyl-lysine recognition domains, thereby preventing the interaction of these proteins with acetylated histones, which disrupts transcriptional regulation.

MS436 is primarily used in biomedical research to study epigenetic regulation and its effects on gene expression. Its applications are pivotal in exploring the mechanisms underlying various diseases, including cancers, where dysregulation of BET proteins is often implicated. Researchers utilize MS436 to elucidate pathways involved in cell cycle regulation, apoptosis, and differentiation. By modulating these pathways, MS436 aids in advancing our understanding of disease pathogenesis, facilitating the development of therapeutic strategies. As such, its use is crucial in preclinical studies that aim to validate the potential therapeutic targets within the epigenetic landscape.

Formula: C₁₈H₁₇N₅O₃S

Purity: Min. 95%

Molecular weight: 383.42 g/mol

Ref: 3D-VFC08425