CAS 139755-85-4

5-(2-ethoxy-5-{[4-(2-hydroxyethyl)piperazin-1-yl]sulfonyl}phenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

Description:

The chemical substance known as 5-(2-ethoxy-5-{[4-(2-hydroxyethyl)piperazin-1-yl]sulfonyl}phenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, with the CAS number 139755-85-4, is a complex organic compound characterized by its multi-functional structure. It features a pyrazolo[4,3-d]pyrimidinone core, which is a bicyclic structure known for its biological activity. The presence of a sulfonyl group and a piperazine moiety suggests potential interactions with biological targets, making it of interest in medicinal chemistry. The ethoxy and hydroxyethyl substituents may enhance solubility and bioavailability, while the methyl and propyl groups contribute to the overall hydrophobic character of the molecule. This compound is likely to exhibit specific pharmacological properties, potentially acting as an inhibitor or modulator in various biochemical pathways. Its synthesis and characterization would involve standard organic chemistry techniques, and it may be evaluated for therapeutic applications in areas such as oncology or neurology, depending on its biological activity profile.

Formula: C₂₃H₃₂N₆O₅S

InChI: InChI=1/C23H32N6O5S/c1-4-6-18-20-21(27(3)26-18)23(31)25-22(24-20)17-15-16(7-8-19(17)34-5-2)35(32,33)29-11-9-28(10-12-29)13-14-30/h7-8,15,30H,4-6,9-14H2,1-3H3,(H,24,25,31)

SMILES: CCCc1c2c(c(=O)[nH]c(c3cc(ccc3OCC)S(=O)(=O)N3CCN(CC3)CCO)n2)n(C)n1

7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-

CAS: 139755-85-4

Formula: C₂₃H₃₂N₆O₅S

Purity: 95%

Color and Shape: Solid

Molecular weight: 504.6024

Ref: IN-DA001BO4

Hydroxyhomosildenafil

CAS: 139755-85-4

Hydroxyhomosildenafil

Purity: 96%

Molecular weight: 504.6g/mol

Ref: 54-OR1023957

Lodenafil

CAS: 139755-85-4

Lodenafil

Purity: ≥98%

Molecular weight: 504.6g/mol

Ref: 54-BUP03698

Hydroxyhomo Sildenafil

CAS: 139755-85-4

Formula: C₂₃H₃₂N₆O₅S

Color and Shape: White To Off-White Solid

Molecular weight: 504.61

Ref: 4Z-S-067

Hydroxyhomosildenafil

CAS: 139755-85-4

Formula: C₂₃H₃₂N₆O₅S

Color and Shape: Neat

Molecular weight: 504.60

Ref: 04-C14232050

Lodenafil

CAS: 139755-85-4

Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)

Formula: C₂₃H₃₂N₆O₅S

Purity: 99.92%

Color and Shape: Solid

Molecular weight: 504.6

Ref: TM-T7346

5-(2-Ethoxy-5-((4-(2-hydroxyethyl)piperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one

CAS: 139755-85-4

Purity: 95.0%

Molecular weight: 504.6099853515625

Ref: 10-F546136

Hydroxyhomo Sildenafil

CAS: 139755-85-4

Applications A Sildenafil (S435000) analog, enhances male sexual function.
References Antunes, J., et al.: Bioorg. Med. Chem., 16, 7599 (2008), Toque, H., et al.: Eur. J. Pharmacol., 591, 189 (2008),

Formula: C₂₃H₃₂N₆O₅S

Color and Shape: Off White Solid

Molecular weight: 504.60

Ref: TR-H942840

Hydroxyhomo sildenafil

CAS: 139755-85-4

Hydroxyhomo sildenafil is a pharmaceutical drug that belongs to the class of pde-5 inhibitors. It is used to treat erectile dysfunction and pulmonary hypertension. The linear calibration curve for hydroxyhomo sildenafil was constructed using human serum at concentrations of 0.5, 1, 2.5, 5, 10, and 20 μM. The LC-MS/MS method showed that the hydroxyl group at C17 was present in all samples analyzed. Bosentan has been found to be an effective treatment for pulmonary hypertension by blocking the activation of phosphodiesterase type-5 (PDE-5). This drug can be detected using an analytical chemistry technique such as gas chromatography mass spectrometry (GC-MS) or liquid chromatography with tandem mass spectrometry (LC-MS/MS).

Formula: C₂₃H₃₂N₆O₅S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 504.6 g/mol

Ref: 3D-FH24359

Hydroxyhomo Sildenafil

CAS: 139755-85-4

Formula: C₂₃H₃₂N₆O₅S

Molecular weight: 504.61

Ref: ST-EA-CP-S2051