CAS 139755-91-2

O-Desethyl Sildenafil

CAS: 139755-91-2

O-Desethyl sildenafil is a metabolite of the phosphodiesterase 5 (PDE5) inhibitor sildenafil .1

Formula: C₂₀H₂₆N₆O₄S

Color and Shape: Solid

Molecular weight: 446.53

Ref: TM-T35601

Sildenafil EP Impurity C (O-Desethyl Sildenafil)

CAS: 139755-91-2

Formula: C₂₀H₂₆N₆O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 446.53

Ref: 4Z-S-0651

Desethyl sildenafil

CAS: 139755-91-2

Desethyl sildenafil

Purity: 98%

Molecular weight: 446.52g/mol

Ref: 54-OR1075413

5-[2-Hydroxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one (Desethylsildenafil)

Controlled Product

CAS: 139755-91-2

Formula: C₂₀H₂₆N₆O₄S

Color and Shape: Neat

Molecular weight: 446.52

Ref: 86-MM0254.22

Sildenafil EP Impurity C

CAS: 139755-91-2

Formula: C₂₀H₂₆N₆O₄S

Molecular weight: 446.52

Ref: ST-EA-CP-S2003

Desethyl Sildenafil

Controlled Product

CAS: 139755-91-2

Impurity Sildenafil EP Impurity C
Applications Desethyl Sildenafil (Sildenafil EP Impurity C) is a metabolite of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.
References Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996); Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998)

Formula: C₂₀H₂₆N₆O₄S

Color and Shape: White

Molecular weight: 446.52

Ref: TR-D289600

Desethyl sildenafil

CAS: 139755-91-2

Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor that is used to treat erectile dysfunction. The compound is not considered hazardous and does not have any known environmental effects. It is primarily metabolized by the liver and excreted in urine. Metabolites are inactive and do not contribute to the pharmacological effect of sildenafil. Sildenafil has been detected in wastewater, although at very low concentrations due to its high water solubility. Matrix effects, such as adsorption onto particulates, can also affect the concentration of active drug in wastewater samples. There are various analytical methods available for measuring sildenafil in wastewater including headspace gas chromatography (HSGC), liquid chromatography-mass spectrometry (LCMS), and liquid chromatography-tandem mass spectrometry (LC-MS/MS). Histology studies have shown that sildenafil does not accumulate in tissues or

Formula: C₂₀H₂₆N₆O₄S

Purity: Min. 95%

Molecular weight: 446.52 g/mol

Ref: 3D-FD21181