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CAS 139755-95-6

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Pyrazole N-Demethyl Sildenafil

Description:
Pyrazole N-Demethyl Sildenafil, identified by its CAS number 139755-95-6, is a chemical compound that is structurally related to sildenafil, a well-known phosphodiesterase type 5 (PDE5) inhibitor used primarily for the treatment of erectile dysfunction and pulmonary arterial hypertension. This compound features a pyrazole ring, which contributes to its pharmacological properties. The N-demethylation aspect indicates that it has undergone a modification where a methyl group is removed from the nitrogen atom, potentially altering its biological activity and pharmacokinetics compared to its parent compound. Pyrazole N-Demethyl Sildenafil may exhibit varying degrees of potency and selectivity for PDE5, influencing its therapeutic efficacy and side effect profile. As with many pharmaceutical compounds, its solubility, stability, and interaction with biological systems are critical for its potential applications. Further research is necessary to fully understand its characteristics, including its mechanism of action, safety profile, and potential therapeutic uses.
Formula:C21H28N6O4S
Synonyms:
  • 1-[[3-(4,7-Dihydroxy-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methyl-piperazine
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