CAS 13977-28-1

Bromadryl

Description:

Bromadryl, with the CAS number 13977-28-1, is an antihistamine that is primarily used for its sedative and anti-allergic properties. It belongs to the class of first-generation antihistamines, which are known for their ability to cross the blood-brain barrier, often resulting in sedative effects. Bromadryl is commonly utilized in the treatment of allergic reactions, hay fever, and cold symptoms, as it helps alleviate symptoms such as sneezing, runny nose, and itching. Its mechanism of action involves blocking the H1 histamine receptors, thereby reducing the physiological effects of histamine in the body. In addition to its antihistaminic effects, Bromadryl may also exhibit anticholinergic properties, which can lead to side effects such as dry mouth, drowsiness, and dizziness. Due to its sedative effects, caution is advised when operating machinery or driving after consumption. As with any medication, it is important to use Bromadryl under the guidance of a healthcare professional to manage potential side effects and interactions with other medications.

Formula: C₁₈H₂₂BrNO·ClH

InChI: InChI=1S/C18H22BrNO.ClH/c1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16;/h4-12H,13-14H2,1-3H3;1H

InChI key: InChIKey=JUOZATSMKDYYGH-UHFFFAOYSA-N

SMILES: C(OCCN(C)C)(C)(C1=CC=C(Br)C=C1)C2=CC=CC=C2.Cl

Synonyms:

• (2-(1-p-Bromophenyl-1-phenylethoxy)ethyl)dimethylethylamine hydrochloride
• 1-(p-Bromophenyl)-1-phenyl-1-(2-dimethylaminoethoxy)ethane hydrochloride
• 2-((p-Bromo-alpha-methyl-alpha-phenylbenzyl)oxy)-N,N-dimethylethylamine hydrochloride
• 2-(1-(4-Bromodiphenyl)ethoxy)-N,N-dimethylethylamine hydrochloride
• 2-(1-(4-Bromophenyl)-1-phenylethoxy)-N,N-dimethylethanamine hydrochloride
• 2-[1-(4-bromophenyl)-1-phenylethoxy]-N,N-dimethylethanaminium chloride
• Bromadryl
• Embramine HCl
• Ethanamine, 2-(1-(4-bromophenyl)-1-phenylethoxy)-N,N-dimethyl-, hydrochloride
• Ethanamine, 2-[1-(4-bromophenyl)-1-phenylethoxy]-N,N-dimethyl-, hydrochloride (1:1)
• Ethylamine, 2-((p-bromo-alpha-methyl-alpha-phenylbenzyl)oxy)-N,N-dimethyl-, hydrochloride
• Ethylamine, 2-[(p-bromo-α-methyl-α-phenylbenzyl)oxy]-N,N-dimethyl-, hydrochloride
• Mebrophenhydramine
• Mebrophenhydramine hydrochloride
• Mebryl
• Unii-7Bj3V657Vc
• beta-Dimethylaminoethyl p-bromo-alpha-methylbenzhydryl ether hydrochloride
• p-Bromo-alpha-methylbenzhydryl 2-dimethylaminoethyl ether hydrochloride

Embramine Hydrochloride

Controlled Product

CAS: 13977-28-1

Stability Hygroscopic
Applications Antihistaminic.
References Berthon, B., et al.: Biochem. Pharmacol., 47, 789 (1994), Hu, Q., et al.: J. Biol. Chem., 274, 33995 (1999),

Formula: C₁₈H₂₂BrNO·ClH

Color and Shape: Neat

Molecular weight: 384.74

Ref: TR-E521000

Embramine hydrochloride

CAS: 13977-28-1

Embramine hydrochloride is a monoethanolamine derivative utilized for its antihistaminic and anticholinergic properties [1].

Formula: C₁₈H₂₃BrClNO

Color and Shape: Solid

Molecular weight: 384.74

Ref: TM-T82476

Embramine Hydrochloride

CAS: 13977-28-1

Color and Shape: Neat

Ref: 61-FOR1971.00