CAS 13977-33-8

Demelverine

Description:

Demelverine, with the CAS number 13977-33-8, is a chemical compound that belongs to the class of antispasmodics. It is primarily used for its muscle-relaxing properties, particularly in the gastrointestinal tract, making it effective in treating conditions associated with smooth muscle spasms. The compound exhibits a mechanism of action that involves the inhibition of phosphodiesterase, leading to increased levels of cyclic AMP, which promotes relaxation of smooth muscle. Demelverine is typically administered in oral form and is known for its relatively low toxicity profile. Its pharmacological effects can include relief from abdominal pain and discomfort caused by spasms. As with many medications, potential side effects may include dizziness, dry mouth, or gastrointestinal disturbances. It is important for users to consult healthcare professionals for appropriate dosing and to discuss any contraindications or interactions with other medications. Overall, demelverine serves as a valuable therapeutic agent in managing specific gastrointestinal disorders.

Formula: C₁₇H₂₁N

InChI: InChI=1S/C17H21N/c1-18(14-12-16-8-4-2-5-9-16)15-13-17-10-6-3-7-11-17/h2-11H,12-15H2,1H3

InChI key: InChIKey=XVWQQNARVMHZBP-UHFFFAOYSA-N

SMILES: C(CN(CCC1=CC=CC=C1)C)C2=CC=CC=C2

Synonyms:

• Benzeneethanamine, N-methyl-N-(2-phenylethyl)-
• Demelverine
• Diphenethylamine, N-methyl-
• Methphenethamine
• N-Methyl-N-(2-phenylethyl)benzeneethanamine
• N-Methyl-β,β′-diphenyldiethylamine
• N-Methylbis(2-phenylethyl)amine
• N-methyl-2-phenyl-N-(2-phenylethyl)ethanamine

Benzeneethanamine, N-methyl-N-(2-phenylethyl)-

CAS: 13977-33-8

Formula: C₁₇H₂₁N

Purity: 95%

Color and Shape: Solid

Molecular weight: 239.3553

Ref: IN-DA001BOS

N-Methyl-N-phenethyl-2-phenylethanamine

CAS: 13977-33-8

Formula: C₁₇H₂₁N

Purity: ≥95%

Molecular weight: 239.362

Ref: 10-F436184

N-Methyl-N-phenethyl-2-phenylethanamine

CAS: 13977-33-8

N-Methyl-N-phenethyl-2-phenylethanamine is a drug that is used to treat depression and diabetic neuropathy. It was first synthesized in the 1930s, but it was not until the 1990s that its antidepressant properties were discovered. NMPEA belongs to a class of drugs called monoamine neurotransmitters, which are chemical messengers that affect mood and behavior. NMPEA also has been shown to be effective against nerve injury, which may be due to its ability to increase the production of nerve growth factor. This drug does not dissolve in water, so it must be reconstituted with an appropriate solvent before use. Reconstitution should occur in a well-ventilated room and gloves should be worn at all times during reconstitution and administration. The recommended dose for oral administration is 2 mg per day administered as 1 mg twice daily or 0.5 mg three times daily.

Formula: C₁₇H₂₁N

Purity: Min. 95%

Color and Shape: Slightly Yellow Clear Liquid

Molecular weight: 239.36 g/mol

Ref: 3D-NAA97733