CAS 1398-78-3

colocynthin

Description:

Colocynthin, with the CAS number 1398-78-3, is a chemical compound derived from the colocynth plant (Citrullus colocynthis), which is known for its medicinal properties. This substance is primarily recognized for its role as a glycoside, exhibiting both laxative and potential anti-inflammatory effects. Colocynthin is characterized by its bitter taste, which is typical of many compounds found in the colocynth plant. It is soluble in water and alcohol, making it accessible for various extraction and formulation processes. The compound has been studied for its pharmacological properties, particularly in traditional medicine, where it has been used to treat digestive disorders. However, caution is advised due to its toxicity at higher doses, which can lead to adverse effects. As with many natural compounds, the therapeutic use of colocynthin requires careful consideration of dosage and potential side effects, emphasizing the importance of further research to fully understand its efficacy and safety profile in clinical applications.

Formula: C₃₈H₅₄O₁₃

InChI: InChI=1S/C38H54O13/c1-18(40)51-33(2,3)13-12-25(42)38(9,48)30-21(41)15-35(6)24-11-10-19-20(37(24,8)26(43)16-36(30,35)7)14-22(31(47)34(19,4)5)49-32-29(46)28(45)27(44)23(17-39)50-32/h10,12-14,20-21,23-24,27-30,32,39,41,44-46,48H,11,15-17H2,1-9H3/b13-12+/t20-,21-,23-,24+,27-,28+,29-,30+,32-,35+,36-,37+,38+/m1/s1

InChI key: InChIKey=QKEJRKXVLGOJMB-YYBMGDPWSA-N

SMILES: C[C@]12[C@]3([C@](C)([C@]4(C(=CC3)C(C)(C)C(=O)C(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)=C4)[H])C(=O)C[C@]1(C)[C@@]([C@@](C(/C=C/C(OC(C)=O)(C)C)=O)(C)O)([C@H](O)C2)[H])[H]

Synonyms:

• (4R,9beta,16alpha,23E)-2-(D-glucopyranosyloxy)-16,20-dihydroxy-9,10,14-trimethyl-1,11,22-trioxo-4,9-cyclo-9,10-secocholesta-2,5,23-trien-25-yl acetate
• (9β,10α,16α,23E)-25-(Acetyloxy)-2-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-16,20-dihydroxy-9-methyl-19-norlanosta-1,5,23-triene-3,11,22-trione
• 19-Nor-9-beta,10-alpha-lanosta-1,5,23-triene-3,11,22-trione, 2-(beta-D-glucopyranosyloxy)-9-methyl-16-alpha,20,25-trihydroxy-, 25-acetate
• 19-Norlanosta-1,5,23-triene-3,11,22-trione, 25-(acetyloxy)-2-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-16,20-dihydroxy-9-methyl-, (9β,10α,16α,23E)-
• 2-O-β-<span class="text-smallcaps">D</span>-Glucopyranosylcucurbitacin E
• Coloside A
• Cucurbitacin E 2-O-β-<span class="text-smallcaps">D</span>-glucopyranoside
• Cucurbitacin E 2-O-β-<span class="text-smallcaps">D</span>-glucoside
• Cucurbitacin E-2-O-glucoside
• Cueg
• Elaterin, 2-beta-glucopyranoside
• Elaterinide
• Gratiotoxin
• Unii-6984R18595
• alpha-Elaterin 2-D-glucopyranoside
• beta-Glucoside de LA curcurbitaine (E)
• α-Elaterin 2-<span class="text-smallcaps">D</span>-glucopyranoside
• Colocynthin
• (9β,10α,16α,23E)-25-(Acetyloxy)-2-(β-D-glucopyranosyloxy)-16,20-dihydroxy-9-methyl-19-norlanosta-1,5,23-triene-3,11,22-trione
• 19-Norlanosta-1,5,23-triene-3,11,22-trione, 25-(acetyloxy)-2-(β-D-glucopyranosyloxy)-16,20-dihydroxy-9-methyl-, (9β,10α,16α,23E)-
• (10α)-25-(Acetyloxy)-2-(β-D-glucopyranosyloxy)-16α,20-dihydroxy-9β-methyl-19-norlanosta-1,5,23-triene-3,11,22-trione
• Elaterinide >=95% (LC/MS-ELSD)
• 2-O-β-D-Glucopyranosylcucurbitacin E
• α-Elaterin 2-D-glucopyranoside
• Cocillana
• 2-O-b-D-Glucopyranosylcucurbitacin E
• Cucurbitacin E 2-O-Glucoside (Elaterinide)

Cucurbitacin E-2-O-glucoside

CAS: 1398-78-3

Cucurbitacin E-2-O-glucoside

Purity: ≥98%

Molecular weight: 718.83g/mol

Ref: 54-BUP01591

Elaterinide

CAS: 1398-78-3

Formula: C₃₈H₅₄O₁₃

Molecular weight: 718.83

Ref: 7W-GK8217

Cucurbitacin E-2-O-glucoside

CAS: 1398-78-3

Cucurbitacin E-2-O-glucoside is a triterpene compound derived from the roots of Citrullus colocynthis that inhibits pro-inflammatory cytokines.

Formula: C₃₈H₅₄O₁₃

Purity: 99.35%

Color and Shape: Solid

Molecular weight: 718.83

Ref: TM-T125931

Cucurbitacin E-2-O-Glucoside

CAS: 1398-78-3

Formula: C₃₈H₅₄O₁₃

Purity: 95%~99%

Molecular weight: 718.837

Ref: BP-BP0417

Cucurbitacin E 2-O-glucoside

CAS: 1398-78-3

Formula: C₃₈H₅₄O₁₃

Molecular weight: 718.84

Ref: 4Z-C-266002

Cucurbitacin e-2-o-glucoside

CAS: 1398-78-3

Natural glycoside

Formula: C₃₈H₅₄O₁₃

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 718.84

Ref: 5G-89613

Cucurbitacin E 2-O-Glucoside (Elaterinide)

Controlled Product

CAS: 1398-78-3

Formula: C₃₈H₅₄O₁₃

Color and Shape: Neat

Molecular weight: 718.828

Ref: TR-C838805

2-O-b-D-Glucopyranosylcucurbitacin E

CAS: 1398-78-3

2-O-b-D-glucopyranosylcucurbitacin E is a natural product that has been isolated from the roots of Cucurbita maxima. This compound has been shown to have bioactive properties, including antioxidant and antimicrobial activity. The extract was tested on chronic cough patients with type 2 diabetes mellitus. The treatment group showed significant improvements in symptoms and bioactive phytochemical levels compared to the control group.
2-O-b-D-glucopyranosylcucurbitacin E is a white powder that is soluble in methanol and water but not in chloroform or ether. It can be analyzed by liquid chromatography, which separates the different components of a sample by passing it through a column filled with an adsorbent material that retains some components more than others.

Formula: C₃₈H₅₄O₁₃

Purity: Min. 95%

Molecular weight: 718.83 g/mol

Ref: 3D-MG157159