CAS 1398609-39-6

Sarolaner

Description:

Sarolaner is an isoxazoline compound primarily used as a veterinary antiparasitic agent, particularly effective against fleas and ticks in dogs and cats. It functions by inhibiting the activity of certain neurotransmitter receptors in the parasites, leading to paralysis and death. Sarolaner is characterized by its high potency and long-lasting effects, providing protection for several weeks after administration. The compound is typically administered orally in the form of chewable tablets, making it convenient for pet owners. Its safety profile is favorable, with minimal side effects reported in treated animals. Sarolaner is also notable for its low toxicity to mammals, which allows for its use in a wide range of animal species. Additionally, it is stable under various environmental conditions, contributing to its effectiveness as a long-term solution for managing parasitic infestations. Overall, Sarolaner represents a significant advancement in veterinary medicine, offering a reliable option for pet owners seeking to protect their animals from ectoparasites.

Synonyms:

• (S)-1-(5'-(5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone
• Ethanone, 1-[5'-[(5S)-5-(3,5-dichloro-4-fluorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]spiro[azetidine-3,1'(3'H)-isobenzofuran]-1-yl]-2-(methylsulfonyl)-
• 1-[6-[(5S)-5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]spiro[1H-2-benzofuran-3,3'-azetidine]-1'-yl]-2-methylsulfonylethanone
• PF 6450567
• Sarolaner(PF-6450567)

Sarolaner

CAS: 1398609-39-6

Sarolaner

Purity: ≥98%

Molecular weight: 581.36g/mol

Ref: 54-BUP05055

Sarolaner

CAS: 1398609-39-6

Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).

Formula: C₂₃H₁₈Cl₂F₄N₂O₅S

Purity: 99.54% - 99.65%

Color and Shape: Solid

Molecular weight: 581.36

Ref: TM-T16845

Sarolaner

CAS: 1398609-39-6

Formula: C₂₃H₁₈Cl₂F₄N₂O₅S

Color and Shape: Neat

Molecular weight: 581.36

Ref: 04-C16908500

Sarolaner 100 µg/mL in Acetonitrile

Controlled Product

CAS: 1398609-39-6

Formula: C₂₃H₁₈Cl₂F₄N₂O₅S

Color and Shape: Single Solution

Molecular weight: 581.36

Ref: 04-A16908500AL-100

Sarolaner

CAS: 1398609-39-6

Formula: C₂₃H₁₈Cl₂F₄N₂O₅S

Molecular weight: 581.36

Ref: 4Z-S-206001

Sarolaner

Controlled Product

CAS: 1398609-39-6

Applications Sarolaner is used in the making of formulations for the control of ticks in cats, and flea infestations in dogs. A parasiiticide.
References Vatta, A. F., et al.: Veterinary Parasitol., 270, S19 (2019), Packianathan, R., et al.: Parasit. Vectors, 10, 387 (2017)

Formula: C₂₃H₁₈Cl₂F₄N₂O₅S

Color and Shape: Off-White

Molecular weight: 581.36

Ref: TR-S141670

Sarolaner

CAS: 1398609-39-6

Sarolaner is a broad-spectrum anthelmintic drug that belongs to the group of control agents. It has been shown to be effective in the treatment of infestations caused by animal parasites, including sanguineus and sanguineus-related species. Sarolaner is active against worms (nematodes and cestodes) in animals and humans, with a wide safety margin. The drug is also effective against gastrointestinal nematodes and lung nematodes. Sarolaner has very low toxicity in animals, which can be attributed to its chemical structure consisting of a bicyclic heterocycle. The drug is administered orally for prevention or treatment of helminthiasis in dogs, cats, cattle, sheep, goats, pigs, horses, rabbits and other animals.

Formula: C₂₃H₁₈Cl₂F₄N₂O₅S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 581.4 g/mol

Ref: 3D-FS180713

Sarolaner

CAS: 1398609-39-6

Purity: 99.05%

Molecular weight: 581.36

Ref: 10-F979702