
CAS 139958-51-3
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Found 3 products.
13-O-Desmethyl tacrolimus
CAS:Tacrolimus is a macrolide immunosuppressant that is used to prevent organ rejection in transplant patients. It binds to the cytosolic protein, FKBP-12, which prevents calcineurin from dephosphorylating and activating nuclear factor of activated T cells (NFAT). Tacrolimus inhibits the production of IL-2 and other cytokines by T cells, suppressing proliferation. Tacrolimus has been shown to be bioequivalent when administered orally or intravenously. Bioavailability may be increased when taken with food.Formula:C43H67NO12Purity:90%MinColor and Shape:PowderMolecular weight:789.99 g/molRef: 4Z-T-3944
Discontinued product


