CAS: 139987-54-5 - (2S)-2-[5-[[(1,2-Dihydro-3-methyl-1-oxobenzo[f]quinazolin-9-yl)methyl]amino]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]pentanedioic acid

Formula: C₂₇H₂₄N₄O₆

InChI: InChI=1S/C27H24N4O6/c1-14-29-21-7-4-16-3-2-15(10-20(16)24(21)25(34)30-14)12-28-18-5-6-19-17(11-18)13-31(26(19)35)22(27(36)37)8-9-23(32)33/h2-7,10-11,22,28H,8-9,12-13H2,1H3,(H,32,33)(H,36,37)(H,29,30,34)/t22-/m0/s1

InChI key: InChIKey=BRVFNEZMTRVUGW-QFIPXVFZSA-N

SMILES: O=C1N=C(NC=2C=CC3=CC=C(C=C3C12)CNC4=CC=C5C(=O)N(CC5=C4)C(C(=O)O)CCC(=O)O)C

Synonyms:

• (2S)-2-(5-{[(3-methyl-1-oxo-1,4-dihydrobenzo[f]quinazolin-9-yl)methyl]amino}-1-oxo-1,3-dihydro-2H-isoindol-2-yl)pentanedioic acid
• (2S)-2-[5-[[(1,2-Dihydro-3-methyl-1-oxobenzo[f]quinazolin-9-yl)methyl]amino]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]pentanedioic acid
• (2s)-2-(5-[[(3-Methyl-1-oxo-1,2-dihydrobenzo[f]quinazolin-9-yl)methyl]amino]-1-oxo-1,3-dihydro-2H-isoindol-2-yl)pentanedioic acid
• (S)-2-(5(((1,2-Dihydro-3-methyl-1-oxobenzo[f]quinazolin-9-yl)methyl)amino)1-oxo-2-isoindolinyl)glutaric acid
• (s)-2-(5-(((3-Methyl-1-oxo-1,2-dihydrobenzo[f]quinazolin-9-yl)methyl)amino)-1-oxoisoindolin-2-yl)pentanedioic acid
• 1843U89
• Benzo[f]quinazoline, pentanedioic acid deriv.
• Bw-1843U89
• Gs-7904
• Gw-1843
• Gw-1843U89
• Osi 7904L
• Osi-7904
• Pentanedioic acid, 2-[5-[[(1,2-dihydro-3-methyl-1-oxobenzo[f]quinazolin-9-yl)methyl]amino]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-, (2S)-
• Pentanedioic acid, 2-[5-[[(1,2-dihydro-3-methyl-1-oxobenzo[f]quinazolin-9-yl)methyl]amino]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-, (S)-

(2S)-2-[5-[[(1,2-Dihydro-3-methyl-1-oxobenzo[f]quinazolin-9-yl)methyl]amino]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]pentanedioic acid

CAS: 139987-54-5

• Formula: C₂₇H₂₄N₄O₆
• Color and Shape: Solid
• Molecular weight: 500.5027

(S)-2-(5-(((3-Methyl-1-oxo-1,2-dihydrobenzo[f]quinazolin-9-yl)methyl)amino)-1-oxoisoindolin-2-yl)pentanedioic acid

CAS: 139987-54-5

(S)-2-(5-(((3-Methyl-1-oxo-1,2-dihydrobenzo[f]quinazolin-9-yl)methyl)amino)-1-oxoisoindolin-2-yl)pentanedioic acid is a pyrimidine compound that inhibits the enzyme thymidylate synthase. This leads to …

• Formula: C₂₇H₂₄N₄O₆
• Purity: Min. 95%
• Molecular weight: 500.5 g/mol

OSI-7904L free acid

CAS: 139987-54-5

OSI-7904L is a folate-based thymidylate synthase inhibitor. It also has antimalarial and antitumor properties.

• Formula: C₂₇H₂₄N₄O₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 500.5