CAS 140-28-3

Benzathine

Description:

Benzathine, with the CAS number 140-28-3, is a chemical compound that belongs to the class of benzyl esters. It is primarily recognized for its use as a long-acting form of penicillin, specifically benzathine penicillin G, which is utilized in the treatment of various bacterial infections, including rheumatic fever and syphilis. Benzathine is characterized by its white to off-white crystalline powder form, which is insoluble in water but soluble in organic solvents. The compound exhibits a relatively low toxicity profile, making it suitable for therapeutic applications. Its pharmacokinetic properties allow for prolonged release and sustained therapeutic effects, which is advantageous in clinical settings. Additionally, benzathine has been studied for its potential applications in other areas, including as a preservative in pharmaceutical formulations. Overall, benzathine's unique properties and efficacy in treating infections underscore its significance in medicinal chemistry.

Formula: C₁₆H₂₀N₂

InChI: InChI=1S/C16H20N2/c1-3-7-15(8-4-1)13-17-11-12-18-14-16-9-5-2-6-10-16/h1-10,17-18H,11-14H2

InChI key: InChIKey=JUHORIMYRDESRB-UHFFFAOYSA-N

SMILES: C(NCCNCC1=CC=CC=C1)C2=CC=CC=C2

Synonyms:

• 1,2-Bis(benzylamino)ethane
• 1,2-Di(Benzylamino)Ethane
• 1,2-Ethanediamine, N,N′-bis(phenylmethyl)-
• 1,2-Ethanediamine, N¹,N²-bis(phenylmethyl)-
• Benzathine
• Benzatin
• Benzyl (2-(benzylamino)ethyl)amine
• Ethylenediamine, N,N′-dibenzyl-
• Ethylenediamine-N,N-Di Benzyl
• N,N'-Bis(phenylmethyl)-1,2-ethanediamine
• N,N-dibenzylethane-1,2-diamine
• N,N′-Dibenzyl-1,2-diaminoethane
• N,N′-Dibenzyl-1,2-ethanediamine
• N,N′-Dibenzyl-1,2-ethylenediamine
• N¹,N²-Bis(phenylmethyl)-1,2-ethanediamine
• NSC 5632
• NSC 62936
• N1,N2-Bis(phenylmethyl)-1,2-ethanediamine
• N,N'Dibenzylethylenediamine
• N,N-Dibenzylethylenediamine

N,N'-Dibenzylethylenediamine

CAS: 140-28-3

Formula: C₁₆H₂₀N₂

Purity: >98.0%(GC)(T)

Color and Shape: White or Colorless to Light orange to Yellow powder to lump to clear liquid

Molecular weight: 240.35

Ref: 3B-D1807

N,N'-Dibenzylethylenediamine, 97%

CAS: 140-28-3

N,N'-Dibenzylethylenediamine is an intermediate of cephalosporin and penicillin. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code

Formula: C₁₆H₂₀N₂

Purity: 97%

Color and Shape: Clear colorless to yellow, Liquid as melt

Molecular weight: 240.35

Ref: 02-L03540

1,2-Ethanediamine, N1,N2-bis(phenylmethyl)-

CAS: 140-28-3

Formula: C₁₆H₂₀N₂

Purity: 95%

Color and Shape: Liquid

Molecular weight: 240.3434

Ref: IN-DA001BWQ

N1,N2-Dibenzylethane-1,2-Diamine

CAS: 140-28-3

N1,N2-Dibenzylethane-1,2-Diamine

Purity: 98%

Molecular weight: 240.35g/mol

Ref: 54-OR1014197

N,N’-Dibenzylethylenediamine

CAS: 140-28-3

Formula: C₁₆H₂₀N₂

Purity: 95%

Color and Shape: Liquid

Molecular weight: 240.35

Ref: 10-F033206

N',N-Dibenzyl-ethylenediamine

CAS: 140-28-3

N',N-Dibenzyl-ethylenediamine is an experimental antibiotic that belongs to the class of antimicrobial agents. It has shown high resistance to penicillin, but is not yet used clinically. N',N-Dibenzyl-ethylenediamine has been shown to exhibit antimicrobial activity against a number of bacterial strains including Streptococcus pyogenes and Escherichia coli. It inhibits the synthesis of proteins by binding to specific nucleotides in DNA, preventing transcription and replication. The mechanism of action of this compound is similar to that of cefapirin sodium and benzathine. N',N-Dibenzyl-ethylenediamine has been shown to be effective against a number of Gram negative bacteria, such as Escherichia coli and Klebsiella pneumoniae, but is ineffective against Gram positive bacteria such as Streptococcus pyogenes or Staphylococcus aureus. This compound also

Formula: C₁₆H₂₀N₂

Purity: Min. 95%

Color and Shape: Colorless Powder

Molecular weight: 240.34 g/mol

Ref: 3D-FD37250

Benzathine

CAS: 140-28-3

Benzathine, a diamine, stabilizes and prolongs penicillin effects in medications like benzathine benzylpenicillin upon injection.

Formula: C₁₆H₂₀N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 240.34

Ref: TM-T20908

Benzathine Diacetate

CAS: 140-28-3

Formula: C₁₆H₂₀N₂·2C₂H₄O₂

Color and Shape: White To Off-White Solid

Molecular weight: 240.35 2 60.05

Ref: 4Z-P-044