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CAS 1400-16-4

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kosotoxin

Description:
Kosotoxin, with the CAS number 1400-16-4, is a potent neurotoxin produced by certain species of the bacterium *Clostridium botulinum*. This substance is classified as a type of botulinum toxin, which is known for its ability to inhibit neurotransmitter release at the neuromuscular junction, leading to muscle paralysis. Kosotoxin is characterized by its high toxicity, with effects that can include respiratory failure and potentially fatal outcomes if ingested or improperly handled. The toxin is a protein composed of heavy and light chains linked by disulfide bonds, which are crucial for its biological activity. Kosotoxin is also sensitive to heat and can be inactivated by proper cooking methods. Due to its extreme toxicity, it is classified as a hazardous substance, and its use is strictly regulated. Research into kosotoxin has implications for both medical applications, such as in the treatment of certain muscle disorders, and for public health, particularly in food safety and bioterrorism preparedness.
Formula:C25H32O8
InChI:InChI=1/C25H32O8/c1-10(2)17(26)15-21(30)14(19(28)12(5)22(15)33-8)9-25(7)23(31)13(6)20(29)16(24(25)32)18(27)11(3)4/h10-11,28-31H,9H2,1-8H3
Synonyms:
  • 6-[2,6-dihydroxy-4-methoxy-3-methyl-5-(2-methylpropanoyl)benzyl]-3,5-dihydroxy-4,6-dimethyl-2-(2-methylpropanoyl)cyclohexa-2,4-dien-1-one
  • Kosotoxin
  • Kosins from hagenia abyssinica
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  • Kosotoxin

    CAS:
    Kosotoxin is a toxin from Hagenia abyssinica. It has been found to be cytotoxic against MAC tumour cells in vivo.
    Formula:C25H32O8
    Color and Shape:Solid
    Molecular weight:460.523