CAS 1400-61-9
:Nystatin
Description:
Nystatin is an antifungal medication primarily used to treat fungal infections, particularly those caused by Candida species. It is a polyene macrolide antibiotic derived from the bacterium Streptomyces noursei. Nystatin exhibits a characteristic yellowish color and is soluble in dimethyl sulfoxide (DMSO) and slightly soluble in water, which limits its systemic use due to potential toxicity. The mechanism of action involves binding to ergosterol, a key component of fungal cell membranes, leading to the formation of pores that disrupt membrane integrity and result in cell death. Nystatin is typically administered topically or orally, depending on the type and location of the infection, and is commonly used in the treatment of oral thrush and skin infections. While generally well-tolerated, it can cause local irritation or allergic reactions in some individuals. Its use is contraindicated in patients with known hypersensitivity to the drug or its components. Overall, Nystatin remains an important agent in the management of superficial fungal infections.
Formula:Unspecified
InChI:InChI=1/C18H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h3-10H,2,11-17H2,1H3,(H,19,20)
SMILES:CCC=CC=CC=CC=CCCCCCCCC(=O)O
Synonyms:- (21E,23E,25E,27E,31E,33E)-20-[(3-amino-3,6-dideoxy-D-mannopyranosyl)oxy]-4,6,8,11,12,16,18,36-octahydroxy-35,37,38-trimethyl-2,14-dioxooxacyclooctatriaconta-21,23,25,27,31,33-hexaene-17-carboxylic acid
- 33-[(3-Amino-3,6-Dideoxyhexopyranosyl)Oxy]-3,4,7,9,11,17,37-Heptahydroxy-15,16,18-Trimethyl-13-Oxo-14,39-Dioxabicyclo[33.3.1]Nonatriaconta-19,21,25,27,29,31-Hexaene-36-Carboxylic Acid
- <span class="text-smallcaps">L</span>-Nystatin
- Biofanal
- Candio-Hermal
- Ceratocide
- Diastatin
- Flagystatin
- Fungicidin
- L-Nystatin
- Moronal (antibiotic)
- Myconystatin
- Mycostatin
- Mycostatin Pastilles
- Mykostatyna
- N-[1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]-4-phenylbutan-2-aminium chloride
- Nilstat
- Nistatin
- Nistatina
- Nyotran
- Nysfungin
- Nystacid
- Nystan
- Nystatin
- Nystatin Suspension Cell Culture Tested
- Nystatin, Streptomyces noursei, Sterile, TC Grade
- Nystatine
- Nystavescent
- Nystex
- Nystop
- O-V Statin
- Octadeca-9,11,13,15-Tetraenoic Acid
- See more synonyms
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Found 18 products.
Nystatin
CAS:<p>Nystatin, 1400-61-9, is a macrolide complex with antifungal and antibiotic properties which exhibits activity against several species of yeast. Learn more.</p>Formula:C47H75NO17Color and Shape:White to pale cream, PowderMolecular weight:926.11THIRD INTERNATIONAL STANDARD FOR NYSTATIN
CAS:<p>THIRD INTERNATIONAL STANDARD FOR NYSTATIN</p>Formula:C18H28O2Molecular weight:276.4137Nystatin
CAS:<p>Aminoglycoside antibiotics</p>Formula:C47H75NO17Color and Shape:Yellow Light Tan PowderMolecular weight:925.5035Nystatin hydrate
CAS:Formula:C47H75NO17·xH2OPurity:≥ 4500U/mg (dried basis)Color and Shape:Yellow to brown-yellow powderMolecular weight:926.09 (anhydrous)Nystatin hydrate, 4400 U/mg, USP grade
CAS:Formula:C47H75NO17·xH2OPurity:≤ 4.0%Color and Shape:Yellow to dark yellow or tan powderMolecular weight:926.09 (anhydrous)Nystatin dihydrate
CAS:<p>Nystatin dihydrate</p>Formula:C47H75NO17·2H2OPurity:By hplc: 91 area-% (Typical Value in Batch COA)Color and Shape: yellow powderMolecular weight:962.12546g/molNystatin
CAS:<p>Nystatin (Fungicidin) is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat</p>Formula:C47H75NO17Purity:69.55% - 99.53%Color and Shape:Yellow SuspensionMolecular weight:926.1Nystatin
CAS:<p>Applications Polyene antifungal antibiotic complex containing 3 biologically active components, A1, A2, A3. Increases the permeability of the cell membrane of sensitive fungi by binding to sterols. Cell culture tested. Growth promotant.Nystatin A1 is shown.<br>References Brautaset, T., et al.: Chem. Biol., 7, 395 (2000), Brautaset, T., et al.: J. Biol. Chem., 278, 14913 (2003), Bruheim, P., et al.: Antimicrob. Agents Chemother., 48, 4120 (2004), Scott, L., et al.: Drugs, 67, 269 (2007),<br></p>Formula:C47H75NO17Color and Shape:NeatMolecular weight:926.09Nystatin
CAS:<p>Nystatin is an antifungal compound, which is produced by the bacterium *Streptomyces noursei*. It functions by binding to ergosterol, a crucial component of fungal cell membranes, creating pores that lead to increased membrane permeability. This disruption results in the leakage of essential cellular components, ultimately causing cell death.</p>Formula:C47H75NO17Purity:Min. 85 Area-%Color and Shape:PowderMolecular weight:926.09 g/moliso-Nystatin
CAS:<p>iso-Nystatin is an antifungal compound, which is derived from the bacterium *Streptomyces noursei*. This specific strain of actinobacteria produces polyene macrolide antifungals, and iso-Nystatin is a derivative that exhibits similar bioactivity as its parent compound, Nystatin. Its mode of action is based on binding ergosterol, a crucial component of fungal cell membranes. This binding disrupts the membrane's structural integrity, inducing pore formation, which leads to ion leakage and ultimately cell lysis and fungal cell death.</p>Formula:C47H75NO17Purity:Min. 95%Molecular weight:926.09 g/molNystatin (Mycostatin) Solution (10000U/ml) for cell culture, Endotoxin (BET) 10.0EU/ml
CAS:Formula:C47H75NO17Color and Shape:Pale yellow to yellow, SuspensionMolecular weight:Â 926.09Nystatin (Mycostatin) for cell culture, 85%, Endotoxin (BET) 0.05EU/mg
CAS:Formula:C47H75NO17Purity:min. 85%Color and Shape:Yellow to slightly brownish, PowderMolecular weight:926.09
