CAS 1401028-24-7

(9R)-N-[(3-Methoxy-2-thienyl)methyl]-9-(2-pyridinyl)-6-oxaspiro[4.5]decane-9-ethanamine

Description:

The chemical substance with the name "(9R)-N-[(3-Methoxy-2-thienyl)methyl]-9-(2-pyridinyl)-6-oxaspiro[4.5]decane-9-ethanamine" and CAS number "1401028-24-7" is a complex organic compound characterized by its unique spirocyclic structure, which includes a combination of a pyridine ring and a thienyl group. This compound features a chiral center at the 9-position, indicating that it can exist in different stereoisomeric forms, which may influence its biological activity and pharmacological properties. The presence of the methoxy and thienyl groups suggests potential interactions with biological targets, making it of interest in medicinal chemistry. Additionally, the oxaspiro framework contributes to its rigidity and may affect its binding affinity and selectivity. The compound's solubility, stability, and reactivity would depend on its functional groups and overall molecular structure, which are critical for its application in drug development or other chemical processes. Further studies would be necessary to elucidate its specific properties and potential uses in various fields.

Formula: C₂₂H₃₀N₂O₂S

InChI: InChI=1S/C22H30N2O2S/c1-25-18-7-15-27-19(18)16-23-13-10-21(20-6-2-5-12-24-20)11-14-26-22(17-21)8-3-4-9-22/h2,5-7,12,15,23H,3-4,8-11,13-14,16-17H2,1H3/t21-/m1/s1

InChI key: InChIKey=DMNOVGJWPASQDL-OAQYLSRUSA-N

SMILES: C(CNCC1=C(OC)C=CS1)[C@@]2(CC3(OCC2)CCCC3)C4=CC=CC=N4

Synonyms:

• TRV-130
• Olinvo
• (9R)-N-[(3-Methoxy-2-thienyl)methyl]-9-(2-pyridinyl)-6-oxaspiro[4.5]decane-9-ethanamine
• TRV 130
• Oliceridine
• 6-Oxaspiro[4.5]decane-9-ethanamine, N-[(3-methoxy-2-thienyl)methyl]-9-(2-pyridinyl)-, (9R)-

Oliceridine-13C-d3

CAS: 1401028-24-7

Formula: C₂₁₁₃CH₂₇D₃N₂O₂S

Molecular weight: 390.56

Ref: 4Z-O-105002

Oliceridine

CAS: 1401028-24-7

Formula: C₂₂H₃₀N₂O₂S

Molecular weight: 386.55

Ref: 4Z-O-105001

Oliceridine

Controlled Product

CAS: 1401028-24-7

Oliceridine is an opioid analgesic that belongs to the group of drugs with low potency. It binds to receptors in the central nervous system and blocks pain signals, providing relief from acute and chronic pain. Oliceridine is also used as a diagnostic agent for patients with suspected drug reactions because it can distinguish between various types of hypersensitivity reactions. Oliceridine has a low incidence of side-effects, which are mainly related to its effects on the liver. The most frequent side-effects are constipation, nausea, vomiting, drowsiness, and headache. Oliceridine has been shown to be effective in patients with hepatic impairment or body mass index (BMI) over 30 kg/m2.

Formula: C₂₂H₃₀N₂O₂S

Purity: Min. 95%

Molecular weight: 386.6 g/mol

Ref: 3D-FO180059

6-Oxaspiro[4.5]decane-9-ethanamine, N-[(3-methoxy-2-thienyl)methyl]-9-(2-pyridinyl)-, (9R)-

CAS: 1401028-24-7

Formula: C₂₂H₃₀N₂O₂S

Molecular weight: 386.5508

Ref: IN-DA001C0I