CAS 1401066-79-2: BMS-906024

Description: BMS-906024, with the CAS number 1401066-79-2, is a small molecule inhibitor primarily known for its role in targeting the protein kinase activity of the enzyme CSF1R (colony-stimulating factor 1 receptor). This compound has garnered attention in the field of cancer research, particularly for its potential therapeutic applications in treating various malignancies by modulating the tumor microenvironment and inhibiting tumor-associated macrophages. BMS-906024 exhibits selective inhibition, which is crucial for minimizing off-target effects and enhancing its efficacy in clinical settings. The compound is typically characterized by its molecular structure, which includes specific functional groups that contribute to its biological activity. Additionally, it has been studied in preclinical models to evaluate its pharmacokinetics, safety profile, and overall effectiveness. As research continues, BMS-906024 may provide insights into novel treatment strategies for cancers that are resistant to conventional therapies.

Formula: C₂₆H₂₆F₆N₄O₃

InChI: InChI=1S/C26H26F6N4O3/c1-36-19-10-6-5-9-18(19)20(15-7-3-2-4-8-15)34-22(24(36)39)35-23(38)17(12-14-26(30,31)32)16(21(33)37)11-13-25(27,28)29/h2-10,16-17,22H,11-14H2,1H3,(H2,33,37)(H,35,38)/t16-,17+,22+/m0/s1

InChI key: InChIKey=AYOUDDAETNMCBW-GSHUGGBRSA-N

SMILES: O=C(N)C(CCC(F)(F)F)C(C(=O)NC1N=C(C=2C=CC=CC2)C=3C=CC=CC3N(C1=O)C)CCC(F)(F)F

BMS-906024

CAS: 1401066-79-2

BMS-906024 (Osugacestat) is a gamma secretase inhibitor, a Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity.

• Formula: C₂₆H₂₆F₆N₄O₃
• Purity: 100% - 99.87%
• Color and Shape: Solid
• Molecular weight: 556.5

BMS 906024

CAS: 1401066-79-2

?-secretase inhibitor; Notch receptor antagonist; antineoplastic

• Formula: C₂₆H₂₆F₆N₄O₃
• Purity: Min. 95%
• Molecular weight: 556.5 g/mol