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CAS 1401284-72-7

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Rapamycin 31,42-Bis(2,2,5-trimethyl-1,3-dioxane-5-carboxylate)

Description:
Rapamycin 31,42-Bis(2,2,5-trimethyl-1,3-dioxane-5-carboxylate), identified by its CAS number 1401284-72-7, is a synthetic derivative of rapamycin, a macrolide compound originally derived from the bacterium *Streptomyces hygroscopicus*. This compound exhibits characteristics typical of rapamycin analogs, including immunosuppressive and anti-proliferative properties, making it of interest in medical research, particularly in the fields of oncology and organ transplantation. The structure features multiple dioxane rings, which contribute to its solubility and stability. The presence of bulky substituents enhances its pharmacological profile, potentially influencing its interaction with the mTOR (mechanistic target of rapamycin) pathway, a critical regulator of cell growth and metabolism. As with many compounds in this class, its efficacy and safety profile are subjects of ongoing research, and it may exhibit varying degrees of bioactivity depending on its formulation and delivery method. Overall, this compound represents a significant area of interest in drug development and therapeutic applications.
Formula:C67H103NO19
Synonyms:
  • Rapamycin 31,42-Bis(2,2,5-trimethyl-1,3-dioxane-5-carboxylate)
  • TemsirolimusImpurity4
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