CAS 140148-25-0

(R)-Ketoprofen acyl-b-D-glucuronide

CAS: 140148-25-0

Ref: 7W-GC9927

(R)-Ketoprofen Acyl-b-D-glucuronide

Controlled Product

CAS: 140148-25-0

Stability Hygroscopic
Applications A metabolite of (R)-Ketoprofen (K200806).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Smith, P., et al.: Drug Metab. Dispos., 1990, 18, 639 (1990), Skordi, E., et al.: Xenobiotica, 34, 1075 (2004),

Formula: C₂₂H₂₂O₉

Color and Shape: Neat

Molecular weight: 430.4

Ref: TR-K200815

(R)-Ketoprofen b-D-glucuronide

CAS: 140148-25-0

(R)-Ketoprofen b-D-glucuronide is a synthetic modified sugar that is produced by the glucuronidation of ketoprofen, a nonsteroidal anti-inflammatory drug. The modification of ketoprofen with glucuronic acid can be achieved through an enzymatic process, which is catalyzed by UDP-glucuronyltransferase. This modification increases the solubility of ketoprofen and its ability to penetrate cells. (R)-Ketoprofen b-D-glucuronide has been shown to have antibacterial properties against Gram positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. It has also shown antiviral activity against HIV-1 due to its inhibition of reverse transcriptase, which is an enzyme important for viral replication.

Formula: C₂₂H₂₂O₉

Purity: Min. 95%

Color and Shape: White to off-white solid.

Molecular weight: 430.4 g/mol

Ref: 3D-MK16769