CAS 140158-49-2

Hippocampal Cholinergic Neurostimulating Peptide

Description:

Hippocampal Cholinergic Neurostimulating Peptide (HCNP) is a neuropeptide that plays a significant role in the modulation of cholinergic signaling in the brain, particularly within the hippocampus, which is crucial for memory and learning processes. This peptide is derived from the precursor protein and is known to influence neuronal activity and synaptic plasticity. HCNP has been studied for its potential neuroprotective effects and its ability to enhance cognitive functions, making it a subject of interest in neuropharmacology and neurodegenerative disease research. The peptide's structure consists of a specific sequence of amino acids that contribute to its biological activity, and it interacts with cholinergic receptors to exert its effects. Research indicates that HCNP may also have implications in the treatment of conditions such as Alzheimer's disease, where cholinergic dysfunction is prevalent. Overall, HCNP represents a promising area of study for understanding cholinergic mechanisms in the brain and developing therapeutic strategies for cognitive impairments.

Formula: C₅₃H₇₉N₁₃O₁₇

InChI: InChI=1/C53H79N13O17/c1-9-26(4)43(65-49(78)36(21-42(71)72)61-46(75)29(7)58-45(74)28(6)57-30(8)68)52(81)64-38(24-67)50(79)60-34(16-17-40(54)69)47(76)62-35(20-31-22-55-33-14-11-10-13-32(31)33)48(77)59-27(5)44(73)56-23-41(70)66-18-12-15-39(66)51(80)63-37(53(82)83)19-25(2)3/h10-11,13-14,22,25-29,34-39,43,55,67H,9,12,15-21,23-24H2,1-8H3,(H2,54,69)(H,56,73)(H,57,68)(H,58,74)(H,59,77)(H,60,79)(H,61,75)(H,62,76)(H,63,80)(H,64,81)(H,65,78)(H,71,72)(H,82,83)/t26-,27-,28-,29-,34-,35-,36-,37-,38-,39-,43-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=N[C@@H](CO)C(=N[C@@H](CCC(=N)O)C(=N[C@@H](Cc1c[nH]c2ccccc12)C(=N[C@@H](C)C(=NCC(=O)N1CCC[C@H]1C(=N[C@@H](CC(C)C)C(=O)O)O)O)O)O)O)O)N=C([C@H](CC(=O)O)N=C([C@H](C)N=C([C@H](C)N=C(C)O)O)O)O

Synonyms:

• N-acetyl-L-alanyl-L-alanyl-L-α-aspartyl-L-isoleucyl-L-seryl-L-glutaminyl-L-tryptophyl-L-alanylglycyl-L-prolyl-L-leucine

Hippocampal Cholinergic Neurostimulating Peptide

CAS: 140158-49-2

Hippocampal Cholinergic Neurostimulating Peptide Ac-Ala-Ala-Asp-Ile-Ser-Gln-Trp-Ala-Gly-Pro-Leu is a peptide hormone that has been found in the hippocampus. It is a cholinergic neurotransmitter that is synthesized and secreted by neurons in the brain. It has been shown to have an effect on bowel disease, locomotor activity, and hippocampal formation. Hippocampal Cholinergic Neurostimulating Peptide Ac-Ala-Ala-Asp-Ile-Ser-Gln-Trp was first identified through biochemical analysis of rat brain tissue.

Formula: C₅₃H₇₉N₁₃O₁₇

Purity: Min. 95%

Molecular weight: 1,170.27 g/mol

Ref: 3D-FH110321