CAS 140158-50-5

2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoic acid

Description:

2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoic acid, commonly referred to as a derivative of amino acids, exhibits several notable characteristics. This compound features an amino group (-NH2), a carboxylic acid group (-COOH), and a unique isoxazole ring that contributes to its biological activity. The presence of the tert-butyl group enhances its lipophilicity, potentially influencing its solubility and permeability in biological systems. The hydroxyl group on the isoxazole ring may participate in hydrogen bonding, affecting the compound's interactions with enzymes or receptors. This substance is often studied for its potential neuroprotective properties and its role as a modulator in various biochemical pathways. Its structural complexity allows for diverse interactions within biological systems, making it a subject of interest in medicinal chemistry and pharmacology. As with many amino acid derivatives, it may also exhibit chirality, which can influence its biological activity and pharmacokinetics. Overall, this compound represents a fascinating intersection of organic chemistry and biochemistry.

Formula: C₁₀H₁₆N₂O₄

InChI: InChI=1S/C10H16N2O4/c1-10(2,3)7-5(8(13)12-16-7)4-6(11)9(14)15/h6H,4,11H2,1-3H3,(H,12,13)(H,14,15)

InChI key: InChIKey=PIXJURSCCVBKRF-UHFFFAOYSA-N

SMILES: C(C(C(O)=O)N)C1=C(C(C)(C)C)ONC1=O

Synonyms:

• (R,S)-Alpha-Amino-3-Hydroxy-5-T-Butyl-4-Isoxazolepropionic Acid
• (R,S)-Atpa
• (Rs)-2-Amino-3-(3-Hydroxy-5-Tert-Butylisoxazol-4-Yl)Propanoic Acid
• (Rs)-A-Amino-3-Hydroxy-5-Tert-Butyl-4-Isoxazolepropionic Acid
• (Rs)-Alpha-Amino-3-Hydroxy-5-Tert-Butyl-4-Isoxazolepropionic Acid
• 2-Amino-3-(5-(tert-butyl)-3-hydroxyisoxazol-4-yl)propanoic acid
• 2-Amino-3-(5-tert-butyl-3-hydroxy-1,2-oxazol-4-yl)propanoic acid
• 2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoic acid
• 2-Ammonio-3-(5-Tert-Butyl-3-Oxo-2,3-Dihydro-1,2-Oxazol-4-Yl)Propanoate
• 4-Isoxazolepropanoic acid, α-amino-5-(1,1-dimethylethyl)-2,3-dihydro-3-oxo-
• Alpha-Amino-3-Hydroxy-5-Tert-Butyl-4-Isoxazolepropionate
• α-Amino-5-(1,1-dimethylethyl)-2,3-dihydro-3-oxo-4-isoxazolepropanoic acid

(S)-ATPA

CAS: 140158-50-5

Formula: C₁₀H₁₆N₂O₄

Molecular weight: 228.3

Ref: 7W-GM9655

ATPA

CAS: 140158-50-5

ATPA activates GluR5 glutamate receptors; EC50s range 0.66-32 μM across GluR5 variants.

Formula: C₁₀H₁₆N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 228.24

Ref: TM-T10405