CAS 140194-24-7

Triptorelin acetate

Description:

Triptorelin acetate is a synthetic peptide and a gonadotropin-releasing hormone (GnRH) analog, primarily used in the treatment of hormone-sensitive conditions such as prostate cancer, endometriosis, and precocious puberty. It functions by initially stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to a temporary increase in sex hormone levels. However, with continuous administration, it causes downregulation of GnRH receptors, resulting in decreased secretion of these hormones and subsequent suppression of testosterone and estrogen production. Triptorelin acetate is characterized by its stability and potency, with a molecular formula that includes multiple amino acids, contributing to its biological activity. It is typically administered via injection and has a relatively long half-life, allowing for less frequent dosing. The compound is also known for its potential side effects, which may include hot flashes, mood changes, and injection site reactions. Overall, Triptorelin acetate is a valuable therapeutic agent in managing various hormone-related disorders.

Formula: C₆₄H₈₂N₁₈O₁₃·C₂H₄O₂

InChI: InChI=1/C64H82N18O13/c1-34(2)23-46(56(88)75-45(13-7-21-69-64(66)67)63(95)82-22-8-14-52(82)62(94)72-31-53(65)85)76-58(90)48(25-36-28-70-42-11-5-3-9-40(36)42)78-57(89)47(24-35-15-17-39(84)18-16-35)77-61(93)51(32-83)81-59(91)49(26-37-29-71-43-12-6-4-10-41(37)43)79-60(92)50(27-38-30-68-33-73-38)80-55(87)44-19-20-54(86)74-44/h3-6,9-12,15-18,28-30,33-34,44-52,70-71,83-84H,7-8,13-14,19-27,31-32H2,1-2H3,(H2,65,85)(H,68,73)(H,72,94)(H,74,86)(H,75,88)(H,76,90)(H,77,93)(H,78,89)(H,79,92)(H,80,87)(H,81,91)(H4,66,67,69)/t44-,45-,46-,47-,48+,49-,50-,51-,52-/m0/s1

Synonyms:

• 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylglycinamide
• Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolyl-
• Triptelin Acetate
• 6-D-Tryptophan Luteinizing HorMone-Releasing Factor (Swine) Acetate
• 6-D-Tryptophan Luteinizing HorMone-Releasing Factor (Pig) Acetate
• Triptorelin Acetate OR Triptorelin PaMoate
• Triptorelin Acetate Q: What is the storage condition of
• Triptorelin Acetate
• OvuGel
• Triptorelin?Acetate impurity
• Triptorelin Acetate Q: What is the CAS Number of
• Decapeptyl-Depot
• BIM 21003C
• Triptorelin AcetateQ: What is
• Triptorelin Acetate Q: What are the applications of

Triptorelin Acetate

CAS: 140194-24-7

Formula: C₆₆H₈₆N₁₈O₁₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 1371.5006

Ref: IN-DA009D11

Triptorelin acetate(57773-63-4 free base)

CAS: 140194-24-7

Triptorelin acetate(57773-63-4 free base)

Purity: ≥98%

Molecular weight: 1371.53g/mol

Ref: 54-BUP10810

Triptorelin acetate 100 µg/mL in Acetonitrile:Methanol

Controlled Product

CAS: 140194-24-7

Formula: C₆₄H₈₂N₁₈O₁₃·C₂H₄O₂

Color and Shape: Single Solution

Molecular weight: 1371.50

Ref: 04-A17893900MC-100

Triptorelin acetate(57773-63-4 free base)

CAS: 140194-24-7

Triptorelin acetate is a GnRH agonist for hormone-responsive cancers, precocious puberty, and assisted reproduction.

Formula: C₆₆H₈₆N₁₈O₁₅

Purity: 99.90%

Color and Shape: White Powder

Molecular weight: 1371.53

Ref: TM-T21410

Triptorelin acetate

Controlled Product

CAS: 140194-24-7

Gonadotropin-releasing hormone agonist

Formula: C₆₄H₈₂N₁₈O₁₃•C₂H₄O₂

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 1,371.5 g/mol

Ref: 3D-FT28582

Triptorelin acetate

CAS: 140194-24-7

Triptorelin is an agonist of gonadotrophin-releasing hormone (GnRH-R). Androgen-deprivation therapy (ADT), based on GnRH agonists and antagonists, is the standard therapeutic approach for prostate cancer (PCa) patients. In castration-resistant prostate cancer (CRPC) GnRH agonists are associated with significant anti-proliferative/pro-apoptotic, anti-metastatic and anti-angiogenic effects, mediated by the Gαi/cAMP signalling cascade. The tryptophan residue in this peptide is replaced with the D-amino acids making the peptide resistant to degradation from proteases and therefore increasing the half-life of the peptide in vivo. Peptide is for research purposes only, strictly not for human use.

Molecular weight: 1,310.6 g/mol

Ref: 3D-CRB1001490

Triptorelin Acetate

CAS: 140194-24-7

Formula: C₆₄H₈₂N₁₈O₁₃C₂H₄O₂

Molecular weight: 1311.47 : 60.1

Ref: ST-EA-CP-T191002