CAS 1402002-76-9
:PF-06442609
Description:
PF-06442609, with the CAS number 1402002-76-9, is a small molecule that has been investigated primarily for its potential therapeutic applications. It is classified as a selective inhibitor of certain protein kinases, which play crucial roles in various cellular processes, including cell growth, division, and survival. The compound is designed to target specific pathways involved in diseases such as cancer and autoimmune disorders. Its chemical structure features functional groups that enhance its binding affinity and selectivity for its target kinases, contributing to its efficacy and safety profile. In preclinical and clinical studies, PF-06442609 has shown promise in modulating disease pathways, although detailed pharmacokinetic and pharmacodynamic properties, as well as specific therapeutic indications, are typically evaluated through rigorous clinical trials. As with many investigational drugs, ongoing research is essential to fully understand its mechanism of action, optimal dosing regimens, and potential side effects in human subjects.
Formula:C24H24F4N4O3
Synonyms:- PF-06442609 >=98% (HPLC)
- PF-06442609
- 2H-Pyrido[1,2-a]pyrazine-1,6-dione, 2-[(1S)-2-[4-fluoro-2-[(1R)-2,2,2-trifluoro-1-methylethyl]phenoxy]-1-methylethyl]-3,4-dihydro-7-(4-methyl-1H-imidazol-1-yl)-
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Found 2 products.
PF-06442609
CAS:<p>PF-06442609 is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the cyclooxygenase enzymes, COX-1 and COX-2, which are responsible for the production of prostaglandins. The inhibition of COX-1 and COX-2 prevents the formation of proinflammatory prostaglandins and decreases pain and inflammation. PF-06442609 has been shown to be safe in human clinical trials. This drug is orally bioavailable and can cross the blood brain barrier, allowing it to reach its targets in the central nervous system. PF-06442609 does not have an effect on protein homeostasis or γ-secretase activity. It has been shown to inhibit isolated heart function in animal studies at high doses.</p>Formula:C24H24F4N4O3Purity:Min. 95%Molecular weight:492.5 g/molPF-06442609
CAS:PF-06442609 is an orally active γ-secretase modulator with an IC50 value of 6 nM for Aβ42. It exhibits good CNS permeability.Formula:C24H24F4N4O3Molecular weight:492.47
