CAS 1402423-29-3

Synthetic drop-in substitute for Digitonin glyco-diosgenin

CAS: 1402423-29-3

Synthetic drop-in substitute for Digitonin glyco-diosgenin

Purity: ≥95%

Molecular weight: 1165.31g/mol

Ref: 54-OR1022556

Glyco-diosgenin

CAS: 1402423-29-3

Glyco-diosgenin is an amphiphilic steroid detergent for extraction, solubilization, purification and Cryo-EM cryo-electron microscopy of membrane proteins.

Formula: C₅₆H₉₂O₂₅

Purity: 99.65%

Color and Shape: Solid

Molecular weight: 1165.31

Ref: TM-T38825

Glyco-diosgenin

CAS: 1402423-29-3

Glyco-diosgenin is an amphipathic molecule that has been found to stabilize proteins. It has the potential to be developed as a drug target for stabilizing proteins in cells. Glyco-diosgenin was synthesized by chemical modification of diosgenin, which is a steroidal saponin found in plants. The chemical modification that occurred at the 3-hydroxyl position of glyco-diosgenin produced a more effective molecule due to increased solubility and decreased toxicity. The protein stabilization properties of glyco-diosgenin have been shown by cryo-electron microscopy on plant cells, titration calorimetry, and functional studies on various proteins.

Formula: C₅₆H₉₂O₂₅

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 1,165.31 g/mol

Ref: 3D-DG63244