CAS 1402727-29-0

Formula: C28H24N4O2

InChI: InChI=1S/C28H24N4O2/c1-33-28-18-26(34-19-25-4-2-3-14-29-25)12-9-22(28)8-11-24-17-23(31-32-24)10-6-20-5-7-21-13-15-30-27(21)16-20/h2-18,30H,19H2,1H3,(H,31,32)/b10-6+,11-8+

InChI key: AMBZHNVCLPHAKA-NSJFVGFPSA-N

SMILES: COC1=C(C=CC(=C1)OCC2=CC=CC=N2)/C=C/C3=CC(=NN3)/C=C/C4=CC5=C(C=C4)C=CN5

PE859

CAS: 1402727-29-0

PE859

Formula: C₂₈H₂₄N₄O₂

Purity: ≥98%

Molecular weight: 448.52

Ref: 54-BUP09397

6-((E)-2-(3-((E)-2-Methoxy-4-(Pyridin-2-Ylmethoxy)Styryl)-1H-Pyrazol-5-Yl)Vinyl)-1H-Indole

CAS: 1402727-29-0

Formula: C₂₈H₂₄N₄O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 448.5158

Ref: IN-DA01EOOF

6-((E)-2-(3-((E)-2-Methoxy-4-(Pyridin-2-Ylmethoxy)Styryl)-1H-Pyrazol-5-Yl)Vinyl)-1H-Indole

CAS: 1402727-29-0

6-((E)-2-(3-((E)-2-Methoxy-4-(Pyridin-2-Ylmethoxy)Styryl)-1H-Pyrazol-5-Yl)Vinyl)-1H-Indole

Formula: C₂₈H₂₄N₄O₂

Purity: 99%

Molecular weight: 448.52

Ref: 54-OR1024174

PE859

CAS: 1402727-29-0

PE859 is a potent inhibitor of both tau and Aβ aggregation.

Formula: C₂₈H₂₄N₄O₂

Purity: 98.8% - 99.09%

Color and Shape: White Solid

Molecular weight: 448.52

Ref: TM-T4077

PE859

CAS: 1402727-29-0

6-((E)-2-(3-((E)-2-Methoxy-4-(pyridin-2-ylmethoxy)styryl)-1H-pyrazol-5-yl)vinyl)-1H-indole

Formula: C₂₈H₂₄N₄O₂

Purity: 99%

Molecular weight: 448.52

Ref: IN-DG627464

PE859

CAS: 1402727-29-0

PE859 is a small molecule that inhibits the activity of the enzyme beta-site amyloid precursor protein cleaving enzyme 1 (BACE1). It has been shown to reduce plaque formation and ameliorate symptoms in an Alzheimer's disease mouse model. PE859 also has antiviral properties, which have been demonstrated using a cell culture system and microscopy studies. The mechanism of action for its antiviral properties is not known, but may be related to its ability to inhibit BACE1 activity.

Formula: C₂₈H₂₄N₄O₂

Purity: Min. 95%

Molecular weight: 448.52 g/mol

Ref: 3D-CGC72729