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CAS 14028-44-5

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Amoxapine

Description:
Amoxapine is a tricyclic antidepressant that is primarily used in the treatment of major depressive disorder. Its chemical structure features a dibenzoxazepine core, which contributes to its pharmacological properties. The substance acts by inhibiting the reuptake of neurotransmitters such as norepinephrine and serotonin, thereby enhancing mood and alleviating depressive symptoms. Amoxapine also exhibits antagonist activity at certain serotonin receptors, which may contribute to its therapeutic effects. In addition to its antidepressant properties, it has been noted for its potential to cause sedation, making it useful in treating anxiety disorders as well. The compound is typically administered orally and is metabolized in the liver, with its metabolites also possessing pharmacological activity. Common side effects may include drowsiness, dry mouth, and weight gain, among others. As with all medications, it is important for patients to be monitored for any adverse effects, especially during the initial stages of treatment.
Formula:C17H16ClN3O
InChI:InChI=1/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2
InChI key:InChIKey=QWGDMFLQWFTERH-UHFFFAOYSA-N
SMILES:ClC=1C=C2C(=NC=3C(OC2=CC1)=CC=CC3)N4CCNCC4
Synonyms:
  • 2-Chloro-11-(1-piperazinyl)dibenz[b,f][1,4]oxazepine
  • 2-Chloro-11-(piperazin-1-yl)dibenzo[b,f][1,4]oxazepine
  • Amoxan
  • Amoxapin
  • Amoxapina
  • Amoxapine
  • Asendin
  • Asendis
  • Cl 67772
  • Demolox
  • See more synonyms
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Found 17 products.
  • Amoxapine

    CAS:
    Formula:C17H16ClN3O
    Purity:>97.0%(GC)(T)
    Color and Shape:White to Orange to Green powder to crystal
    Molecular weight:313.79

    Ref: 3B-A2499

    1g
    133.00€
  • 2-Chloro-11-(1-piperazinyl)dibenzo[b,f]-1,4-oxazepine, 98%

    CAS:
    <p>A tricyclic norepinephrine uptake inhibitor</p>
    Formula:C17H16ClN3O
    Purity:98%
    Molecular weight:313.78

    Ref: 02-J64066

    1g
    208.00€
    5g
    To inquire
    250mg
    67.00€
  • Amoxapine, 1mg/ml in Methanol

    CAS:
    Color and Shape:Single Solution

    Ref: LP-AMX-1900-FB-1LM

    1ml
    111.00€
  • Amoxapine

    CAS:
    <p>Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi</p>
    Formula:C17H16ClN3O
    Color and Shape:White Off-White Powder
    Molecular weight:313.09819
  • 2-Chloro-11-(1-piperazinyl)dibenz[b,f][1,4]oxazepine

    CAS:
    Formula:C17H16ClN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:313.7814

    Ref: IN-DA001C87

    1g
    210.00€
    5g
    512.00€
    50mg
    71.00€
    100mg
    64.00€
    250mg
    111.00€
  • Amoxapine

    CAS:
    <p>Amoxapine (CL-67772) exerts its antidepressant effect by inhibiting the re-uptake of norepinephrine and, to a lesser degree, of serotonin, at adrenergic nerve</p>
    Formula:C17H16ClN3O
    Purity:98.25% - 98.80%
    Color and Shape:Solid
    Molecular weight:313.78
  • Amoxapine

    CAS:
    Formula:C17H16ClN3O
    Color and Shape:Pale Yellow Solid
    Molecular weight:313.79

    Ref: 4Z-A-198001

    5mg
    To inquire
    10mg
    349.00€
    25mg
    444.00€
    50mg
    635.00€
    100mg
    To inquire
  • Amoxapine

    CAS:
    <p>Amoxapine</p>
    Purity:98%
    Molecular weight:313.78g/mol

    Ref: 54-OR1026955

    1g
    152.00€
    5g
    659.00€
    25g
    3,072.00€
    100mg
    47.00€
    250mg
    78.00€
  • Amoxapine

    CAS:
    <p>Amoxapine</p>
    Purity:≥98%
    Molecular weight:313.78g/mol

    Ref: 54-BUP18093

    100mg
    53.00€
    500mg
    98.00€
  • Amoxapine

    Controlled Product
    CAS:
    Formula:C17H16ClN3O
    Color and Shape:Neat
    Molecular weight:313.78

    Ref: 04-C10242400

    100mg
    77.00€
  • Amoxapine

    CAS:
    Color and Shape:Neat

    Ref: 86-MM1773.00

    250mg
    To inquire
  • Amoxapine

    CAS:
    Color and Shape:Neat

    Ref: LP-AMX-1900-FB-10

    10mg
    201.00€
    50mg
    To inquire
    100mg
    To inquire
  • Amoxapine

    CAS:
    Formula:C17H16ClN3O
    Molecular weight:313.78

    Ref: 7W-GP2126

    100mg
    69.00€
  • Amoxapine

    CAS:
    <p>Applications Antidepressant.<br>References Takahashi, R., et al.: J. Int. Med. Res., 7, 7 (1979), Jue, S.G., et al.: Drugs 24, 1 (1982)<br></p>
    Formula:C17H16ClN3O
    Color and Shape:White To Light Beige
    Molecular weight:313.78

    Ref: TR-A634230

    1g
    174.00€
    10g
    1,324.00€
    100mg
    93.00€
  • Amoxapine - Bio-X ™

    Controlled Product
    CAS:
    <p>Amoxapine is a dibenzoxazepine- derivative tricyclic antidepressant or TCA. It is used in the treatment of depressive disorders and psychotic depression. Amoxapine is a potent serotonin and norepinephrine reuptake inhibitor. It works on the central nervous system to increase levels of the chemicals in the brain.</p>
    Formula:C17H16ClN3O
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:313.78 g/mol

    Ref: 3D-BA164170

    25mg
    135.00€
  • Amoxapine

    Controlled Product
    CAS:
    <p>Serotonin (5-HT2) receptor antagonist; inhibits norepinephrine reuptake</p>
    Formula:C17H16ClN3O
    Purity:Min. 98 Area-%
    Color and Shape:White Powder
    Molecular weight:313.78 g/mol

    Ref: 3D-FA17884

    1g
    240.00€
    2g
    320.00€
    5g
    468.00€
    10g
    601.00€
    25g
    759.00€
  • Amoxapine

    CAS:
    Color and Shape:Neat

    Ref: 61-FOR1773.00

    10mg
    Discontinued
    Discontinued product