CAS 1402837-79-9

(αR,5R)-6-Fluoro-α-(trans-4-hydroxycyclohexyl)-5H-imidazo[5,1-a]isoindole-5-ethanol

Description:

The chemical substance known as (αR,5R)-6-Fluoro-α-(trans-4-hydroxycyclohexyl)-5H-imidazo[5,1-a]isoindole-5-ethanol, with the CAS number 1402837-79-9, is a complex organic compound characterized by its unique structural features. It contains an imidazoisoindole core, which is a bicyclic structure that contributes to its potential biological activity. The presence of a fluorine atom at the 6-position and a hydroxyl group at the trans-4-position of the cyclohexyl moiety suggests that this compound may exhibit interesting pharmacological properties, possibly influencing its interaction with biological targets. The stereochemistry indicated by the (αR,5R) configuration implies specific spatial arrangements that can significantly affect the compound's reactivity and binding affinity. Additionally, the presence of an ethanol functional group may enhance its solubility and bioavailability. Overall, this compound's intricate structure and functional groups suggest potential applications in medicinal chemistry, particularly in the development of therapeutic agents. Further studies would be necessary to elucidate its specific properties and biological activities.

Formula: C₁₈H₂₁FN₂O₂

InChI: InChI=1S/C18H21FN2O2/c19-14-3-1-2-13-16-9-20-10-21(16)15(18(13)14)8-17(23)11-4-6-12(22)7-5-11/h1-3,9-12,15,17,22-23H,4-8H2/t11-,12-,15-,17-/m1/s1

InChI key: InChIKey=YGACXVRLDHEXKY-GADXADSLSA-N

SMILES: C([C@@H](O)[C@]1(CC[C@H](O)CC1)[H])[C@@H]2C=3C(C=4N2C=NC4)=CC=CC3F

Synonyms:

• 5H-Imidazo[5,1-a]isoindole-5-ethanol, 6-fluoro-α-(trans-4-hydroxycyclohexyl)-, (αR,5R)-
• (αR,5R)-6-Fluoro-α-(trans-4-hydroxycyclohexyl)-5H-imidazo[5,1-a]isoindole-5-ethanol

IDO-IN-5

CAS: 1402837-79-9

IDO-IN-5 is a peptide inhibitor with a molecular weight of 1064.55 Da and CAS number 1402837-79-9. It is used as a research tool in cell biology, pharmacology, and other life sciences. IDO-IN-5 specifically inhibits the activity of the enzyme indoleamine 2,3 dioxygenase (IDO), which is involved in the production of tryptophan from the amino acid L-tryptophan. The IDO enzyme regulates the production of other substances that are important for immune response. As an inhibitor, IDO-IN-5 blocks this pathway and prevents immune cells from being stimulated. This inhibition can be reversed by adding L-tryptophan to cells treated with IDO-IN-5.

Formula: C₁₈H₂₁FN₂O₂

Purity: Min. 95%

Molecular weight: 316.37 g/mol

Ref: 3D-CGC83779

IDO-IN-5

CAS: 1402837-79-9

IDO-IN-5 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM).

Formula: C₁₈H₂₁FN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 316.37

Ref: TM-T11619