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CAS 1403-17-4

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Candicidin

Description:
Candicidin is a polyene macrolide antibiotic produced by the fermentation of certain strains of Streptomyces species, particularly Streptomyces griseus. It is primarily known for its antifungal properties, making it effective against a variety of fungal infections. The structure of candicidin features a large lactone ring with multiple conjugated double bonds, which is characteristic of polyene antibiotics. This structural feature is crucial for its mechanism of action, as it interacts with fungal cell membranes, leading to increased permeability and ultimately cell death. Candicidin is typically used in clinical settings to treat infections caused by fungi, particularly those resistant to other antifungal agents. However, its use may be limited due to potential toxicity and side effects, necessitating careful consideration in therapeutic applications. Additionally, candicidin's effectiveness can be influenced by factors such as the specific fungal strain and the presence of resistance mechanisms. Overall, candicidin represents an important class of antifungal agents with significant clinical relevance.
Formula:Unspecified
InChI:InChI=1/C59H84N2O18/c1-35-18-15-13-11-9-7-5-6-8-10-12-14-16-21-47(78-59-56(74)54(61)55(73)38(4)77-59)33-51(71)53(58(75)76)50(70)31-46(67)30-45(66)29-44(65)28-43(64)27-41(62)19-17-20-42(63)32-52(72)79-57(35)37(3)26-36(2)48(68)34-49(69)39-22-24-40(60)25-23-39/h5-16,18,21-25,35-38,43-45,47-48,50-51,53-57,59,64-66,68,70-71,73-74H,17,19-20,26-34,60-61H2,1-4H3,(H,75,76)/b6-5+,9-7+,10-8+,13-11+,14-12+,18-15+,21-16+/t35?,36?,37?,38-,43?,44?,45?,47?,48?,50?,51?,53?,54+,55-,56+,57?,59?/m1/s1
Synonyms:
  • (23E,25E,27E,29E,31E,33E,35E)-22-[(3-amino-3,6-dideoxy-D-mannopyranosyl)oxy]-38-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-10,12,14,18,20-pentahydroxy-37-methyl-2,4,8,16-tetraoxooxacyclooctatriaconta-23,25,27,29,31,33,35-heptaene-19-carboxylic acid
  • Candeptin
  • Candicidin [USAN:INN:BAN]
  • Candicidina
  • Candicidina [INN-Spanish]
  • Candicidine
  • Candicidine [INN-French]
  • Candicidinum
  • Candicidinum [INN-Latin]
  • Candimon
  • See more synonyms
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Found 1 products.
  • Candicidin
    Targetmol
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    Candicidin

    CAS:
    <p>Candicidin, a heptaene macrolide from S. griseus or A. levoris, treats candidiasis topically. Mainly candicidin D.</p>
    Formula:C59H84N2O18
    Purity:98%
    Color and Shape:Coa
    Molecular weight:1109.317

    Ref: TM-T25202