CAS 1403-66-3

Gentamicin

Description:

Gentamicin is an aminoglycoside antibiotic that is primarily used to treat various bacterial infections, particularly those caused by Gram-negative bacteria. It is derived from the bacterium Micromonospora purpurea and is known for its broad-spectrum antimicrobial activity. Gentamicin works by inhibiting bacterial protein synthesis, which ultimately leads to cell death. The substance is typically administered via injection or topical application, as it is poorly absorbed from the gastrointestinal tract. Its chemical structure features multiple amino groups, contributing to its solubility in water and its ability to penetrate bacterial cell membranes. Gentamicin is often used in clinical settings for serious infections, including those affecting the respiratory tract, urinary tract, and bloodstream. However, it is important to monitor its use due to potential nephrotoxicity and ototoxicity, which can occur with prolonged exposure or high doses. Overall, gentamicin remains a critical tool in the treatment of severe bacterial infections, particularly in hospital settings.

Formula: Unspecified

InChI: InChI=1/C21H43N5O7.C20H41N5O7.C19H39N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(2,28)7-29-19;1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;8-19,25-28H,4-7,21-24H2,1-3H3;8-18,24-27H,3-7,20-23H2,1-2H3;(H2,1,2,3,4)/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+;8-,9-,10+,11-,12+,13+,14-,15-,16+,17-,18-,19-,20+;8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m110./s1

InChI key: CEAZRRDELHUEMR-UHFFFAOYSA-N

SMILES: CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC

Synonyms:

• Centicin
• Gentacycol
• Gentalline
• Gentamicina
• Gentamicine
• Gentamycin
• Gentamycins
• Gentavet
• Lyramycin
• Oksitselanim
• Septigen
• (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranoside
• (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-[(1R)-1-aminoethyl]tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-5-methyl-4-methylamino-tetrahydropyran-3,5-diol
• (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-[(1R)-1-methylaminoethyl]tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-5-methyl-4-methylamino-tetrahydropyran-3,5-diol
• Gentamicin
• sulfuric acid
• (3R,4R,5R)-2-[(1S,2S,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(1-methylaminoethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-5-methyl-4-methylamino-tetrahydropyran-3,5-diol
• (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(aminomethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-5-methyl-4-methylamino-tetrahydropyran-3,5-diol

Gentamicin

CAS: 1403-66-3

Formula: C₂₁H₄₃N₅O₇

Color and Shape: Solid

Molecular weight: 477.5954

Ref: IN-DA001C92

Gentamicin

CAS: 1403-66-3

Gentamicin

Purity: 98%

Ref: 54-OR1023144

Gentamicin

CAS: 1403-66-3

Gentamicin (Centicin) is a broad-spectrum aminoglycoside antibiotic with antibacterial activity, can be used to study ocular infections.

Formula: C₂₁H₄₃N₅O₇

Color and Shape: Yellow Solid

Molecular weight: 477.60(Avervage)

Ref: TM-T25447

Gentamicin

CAS: 1403-66-3

Formula: C₂₁H₄₃N₅O₇

Molecular weight: 477.59

Ref: ST-EA-CP-G33019