CAS 1404-88-2: Tyrothricin
Description:Tyrothricin is a complex mixture of polypeptides and is primarily known for its antibiotic properties. It is produced by the bacterium Bacillus cereus and is effective against a range of Gram-positive bacteria, making it valuable in clinical applications, particularly in topical formulations. Tyrothricin exhibits a unique mechanism of action by disrupting bacterial cell membranes, leading to cell lysis. The substance is typically used in the treatment of localized infections and is often found in throat lozenges and topical ointments. It is characterized by its low solubility in water, which limits its systemic absorption and reduces the risk of systemic side effects. Tyrothricin is generally well-tolerated, but like all antibiotics, it may lead to allergic reactions in some individuals. Its use is often limited to specific applications due to the potential for developing antibiotic resistance. Overall, tyrothricin remains an important compound in the field of antimicrobial therapy, particularly for treating infections caused by susceptible bacteria.
Formula:Unspecified
InChI:InChI=1/C65H85N11O13/c1-38(2)32-49-60(84)74-52(36-42-20-12-7-13-21-42)65(89)76-31-15-23-53(76)63(87)73-51(34-41-18-10-6-11-19-41)61(85)70-47(33-40-16-8-5-9-17-40)57(81)48(37-54(67)78)71-59(83)46(28-29-55(79)80)68-50(35-43-24-26-44(77)27-25-43)62(86)75-56(39(3)4)64(88)69-45(22-14-30-66)58(82)72-49/h5-13,16-21,24-27,38-39,45-53,56,68,77H,14-15,22-23,28-37,66H2,1-4H3,(H2,67,78)(H,69,88)(H,70,85)(H,71,83)(H,72,82)(H,73,87)(H,74,84)(H,75,86)(H,79,80)/t45-,46-,47+,48-,49-,50-,51-,52+,53-,56-/m0/s1
- Synonyms:
- 3-[(3S,6R,8S,11S,13S,16S,19S,22S,25R,30aS)-8-(2-amino-2-oxoethyl)-19-(3-aminopropyl)-3,6,25-tribenzyl-13-(4-hydroxybenzyl)-22-(2-methylpropyl)-1,4,7,10,14,17,20,23,26-nonaoxo-16-(propan-2-yl)triacontahydropyrrolo[2,1-f][1,4,7,10,13,16,19,22,25]nonaazacyclooctacosin-11-yl]propanoic acid
- An antibacterial substance produced by the growth of Bacillus brevis Dubos (Fam. Bacteriaceae)
- Bactratycin
- Biothricin
- Caswell No. 900A
- Coltirot
- Dermotricine
- Dubos crude crystals
- EPA Pesticide Chemical Code 006311
- Ginotricina
- See more synonyms
- Hydrotricine
- Intraderm tyrothricin
- Martricin
- Pharothricetten
- Rinotricina
- Solutricine
- Tirotricina
- Tirotricina [INN-Spanish]
- Triciderm
- Tyrex
- Tyri 10
- Tyroderm
- Tyrosur
- Tyrothricin [INN:BAN]
- Tyrothricine
- Tyrothricine [INN-French]
- Tyrothricinum
- Tyrothricinum [INN-Latin]
- Tyrozets
- Tyrothricin
