CAS 1404-88-2

Tyrothricin

Description:

Tyrothricin is a complex mixture of polypeptides and is primarily known for its antibiotic properties. It is produced by the bacterium Bacillus cereus and is effective against a range of Gram-positive bacteria, making it valuable in clinical applications, particularly in topical formulations. Tyrothricin exhibits a unique mechanism of action by disrupting bacterial cell membranes, leading to cell lysis. The substance is typically used in the treatment of localized infections and is often found in throat lozenges and topical ointments. It is characterized by its low solubility in water, which limits its systemic absorption and reduces the risk of systemic side effects. Tyrothricin is generally well-tolerated, but like all antibiotics, it may lead to allergic reactions in some individuals. Its use is often limited to specific applications due to the potential for developing antibiotic resistance. Overall, tyrothricin remains an important compound in the field of antimicrobial therapy, particularly for treating infections caused by susceptible bacteria.

Formula: Unspecified

InChI: InChI=1/C65H85N11O13/c1-38(2)32-49-60(84)74-52(36-42-20-12-7-13-21-42)65(89)76-31-15-23-53(76)63(87)73-51(34-41-18-10-6-11-19-41)61(85)70-47(33-40-16-8-5-9-17-40)57(81)48(37-54(67)78)71-59(83)46(28-29-55(79)80)68-50(35-43-24-26-44(77)27-25-43)62(86)75-56(39(3)4)64(88)69-45(22-14-30-66)58(82)72-49/h5-13,16-21,24-27,38-39,45-53,56,68,77H,14-15,22-23,28-37,66H2,1-4H3,(H2,67,78)(H,69,88)(H,70,85)(H,71,83)(H,72,82)(H,73,87)(H,74,84)(H,75,86)(H,79,80)/t45-,46-,47+,48-,49-,50-,51-,52+,53-,56-/m0/s1

Synonyms:

• 3-[(3S,6R,8S,11S,13S,16S,19S,22S,25R,30aS)-8-(2-amino-2-oxoethyl)-19-(3-aminopropyl)-3,6,25-tribenzyl-13-(4-hydroxybenzyl)-22-(2-methylpropyl)-1,4,7,10,14,17,20,23,26-nonaoxo-16-(propan-2-yl)triacontahydropyrrolo[2,1-f][1,4,7,10,13,16,19,22,25]nonaazacyclooctacosin-11-yl]propanoic acid
• An antibacterial substance produced by the growth of Bacillus brevis Dubos (Fam. Bacteriaceae)
• Bactratycin
• Biothricin
• Caswell No. 900A
• Coltirot
• Dermotricine
• Dubos crude crystals
• EPA Pesticide Chemical Code 006311
• Ginotricina
• Hydrotricine
• Intraderm tyrothricin
• Martricin
• Pharothricetten
• Rinotricina
• Solutricine
• Tirotricina
• Tirotricina [INN-Spanish]
• Triciderm
• Tyrex
• Tyri 10
• Tyroderm
• Tyrosur
• Tyrothricin [INN:BAN]
• Tyrothricine
• Tyrothricine [INN-French]
• Tyrothricinum
• Tyrothricinum [INN-Latin]
• Tyrozets

TYROTHRICIN CRS

CAS: 1404-88-2

TYROTHRICIN CRS

Formula: C₆₅H₈₅N₁₁O₁₃

Molecular weight: 1228.436

Ref: 41-T3000000

Tyrothricin

CAS: 1404-88-2

Formula: C₁₆₅H₂₂₇N₃₃O₃₀

Purity: 96.0%

Color and Shape: Solid

Molecular weight: 3152.7710

Ref: IN-DA001CD2

Tyrothricin

CAS: 1404-88-2

Formula: C₆₅H₈₅N₁₁O₁₃

Color and Shape: White to off-white powder

Molecular weight: 1228.44

Ref: 7W-GK8465

Tyrothricin

CAS: 1404-88-2

Formula: C₉₉H₁₄₀N₂₀O₁₇·C₆₆H₈₇N₁₃O₁₃

Color and Shape: White To Off-White Solid

Molecular weight: 1882.34 1270.51

Ref: 4Z-T-231001

Tyrothricin

CAS: 1404-88-2

Tyrothricin is a natural polypeptide antibiotic, a mixture of gramicidin and tyrocidine, disrupting cell membranes of Gram-positive bacteria, skin infection.

Purity: 98%

Color and Shape: Solid

Molecular weight: N/A

Ref: TM-T17185

Tyrothricin

CAS: 1404-88-2

Tyrothricin is a peptide antibiotic, which is derived from the bacterium Bacillus brevis. This compound comprises a mixture of polypeptides, primarily gramicidin and tyrocidine, both of which are instrumental in its antimicrobial activity. The mode of action of tyrothricin involves disrupting bacterial cell membranes, leading to cell lysis and death. Gramicidin increases the permeability of the bacterial membrane to ions, while tyrocidine promotes disruption of membrane integrity, which together exert bactericidal and bacteriostatic effects.

Formula: C₆₅H₈₅N₁₁O₁₃

Purity: Min. 95%

Molecular weight: 1,228.44 g/mol

Ref: 3D-AT30150