CAS 1404-93-9
:Vancomycin, hydrochloride
Description:
Vancomycin hydrochloride is a glycopeptide antibiotic primarily used to treat serious bacterial infections, particularly those caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It is characterized by its complex structure, which includes a series of amino acids and sugar moieties that contribute to its mechanism of action. Vancomycin works by inhibiting cell wall synthesis in bacteria, ultimately leading to cell lysis and death. The hydrochloride form enhances its solubility in water, making it suitable for intravenous administration. It is typically administered in a clinical setting due to its potency and the need for monitoring potential side effects, such as nephrotoxicity and ototoxicity. Vancomycin is also notable for its spectrum of activity, which is limited to certain types of bacteria, and it is often reserved for cases where other antibiotics are ineffective. Its use is guided by susceptibility testing to ensure effectiveness and to combat the development of antibiotic resistance.
Formula:C66H75Cl2N9O24·xClH
InChI:InChI=1S/C66H75Cl2N9O24.ClH/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92;/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95);1H/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-;/m0./s1
InChI key:InChIKey=LCTORFDMHNKUSG-XTTLPDOESA-N
SMILES:O(C=1C2=CC3=CC1OC=4C(Cl)=CC(=CC4)[C@@H](O)[C@@H](NC([C@@H](CC(C)C)NC)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@]3(C(=O)N[C@@]5(C=6C=C(C=7C([C@@H](C(O)=O)NC(=O)[C@]([C@H](O)C=8C=C(Cl)C(O2)=CC8)(NC5=O)[H])=CC(O)=CC7O)C(O)=CC6)[H])[H])[C@H]9[C@H](O[C@H]%10C[C@](C)(N)[C@H](O)[C@H](C)O%10)[C@@H](O)[C@H](O)[C@@H](CO)O9.Cl
Synonyms:- (1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid hydrochloride (non-preferred name)
- (1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2~3,6~.2~14,17~.1~8,12~.1~29,33~.0~10,25~.0~34,39~]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid (non-preferred name)
- (3S-(3R*,6S*(S*),7S*,22S*,23R*,26R*,36S*,38aS*))-3-(2-Amino-2-oxoethyl)-44-((2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl)oxy)-10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-((4-methyl-2-(methylamino)-1-oxopentyl)amino)-2,5,24,38,39-pentaoxo-22H-8,11:18,21-dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-(1,6,9)oxadiazacyclohexadecino(4,5-m)(10,2,16)benzoxadiazacyclotetracosine-26-carboxylic acid, monohydrochloride
- 22H-8,11:18,21-Dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine, vancomycin deriv.
- 48-({3-[(4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl}oxy)-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2~3,6~.2~14,17~.1~8,12~.1~29,33~.0~10,25~.0~34,39~]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid hydrochloride (1:1) (non-preferred name)
- Laikexin
- Lyphocin
- Unii-71Wo621Tjd
- Vancocin hydrochloride
- Vancocine hydrochloride
- Vancocyn
- Vancomycin HCl
- Vancomycin monohydrochloride
- Vancor
- See more synonyms
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Vancomycin hydrochloride, Molecular Biology Grade
CAS:Vancomycin hydrochloride, 1404-93-9, is a polypeptide with antibiotic properties suitable for laboratory study of bacterial infections. Learn more at Thermo Fisher Scientific.
Formula:C66H76Cl3N9O24Color and Shape:White to tan to brown, Free-flowing powderMolecular weight:1485.72Vancomycin hydrochloride, 50 mg/ml in distilled water, sterile-filtered
CAS:This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci
SECOND INTERNATIONAL STANDARD FOR VANCOMYCIN
CAS:SECOND INTERNATIONAL STANDARD FOR VANCOMYCINFormula:C66H75Cl2N9O24Molecular weight:1449.254VANCOMYCIN HYDROCHLORIDE CRS
CAS:VANCOMYCIN HYDROCHLORIDE CRSFormula:C66H75Cl2N9O24Color and Shape:White. Powder.Molecular weight:1449.254Vancomycin B
CAS:Antibiotics nesoiFormula:C66H75Cl2N9O24·HClColor and Shape:White Brown PowderMolecular weight:1483.40688Vancomycin B with Monodechlorovancomycin
CAS:Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoiFormula:C66H75Cl2N9O24·HClColor and Shape:Off-White Tan PowderMolecular weight:1483.40688Vancomycin, hydrochloride
CAS:Formula:C66H76Cl3N9O24Purity:95%Color and Shape:SolidMolecular weight:1485.7145Vancomycin hydrochloride
CAS:Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!Formula:C66H76Cl3N9O24Purity:97.20% - 99.19%Color and Shape:Off White PowderMolecular weight:1485.71Vancomycin hydrochloride
CAS:Vancomycin hydrochlorideFormula:C66H75Cl2N9O24·ClHPurity:Heavy metals: <30 ppm. (Typical Value in Batch COA)Color and Shape: white. almost white or tan to brown free flowing powderMolecular weight:1,485.71g/molVancomycin hydrochloride, low endotoxin
CAS:Formula:C66H75Cl2N9O24·HClPurity:≤ 5.0%Color and Shape:White to tan powderMolecular weight:1485.73Vancomycin hydrochloride BioChemica
CAS:Vancomycin hydrochloride BioChemicaColor and Shape:SolidMolecular weight:1,485.71g/molVancomycin hydrochloride
CAS:Formula:C66H75Cl2N9O24·HClPurity:≤ 5.0%Color and Shape:White to tan powderMolecular weight:1485.73Vancomycin hydrochloride (Standard)
CAS:Vancomycin hydrochloride (Standard) is the standard substance of Vancomycin hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Vancomycin hydrochloride (Vancomycin HCl) is a glycopeptide antibiotic that targets Peptidoglycan in bacterial cell wall synthesis. Vancomycin hydrochloride is mainly used for the treatment of severe Gram-positive bacterial infections.Formula:C66H76Cl3N9O24Color and Shape:Off White PowderMolecular weight:1485.71Vancomycin hydrochloride
CAS:Controlled ProductFormula:C66H75Cl2N9O24·ClHColor and Shape:NeatMolecular weight:1485.71Vancomycin Hydrochloride
CAS:Controlled ProductFormula:C66H75Cl2N9O24·ClHColor and Shape:Off White SolidMolecular weight:1485.71Vancomycin Hydrochloride (90%)
CAS:Stability Hygroscopic
Applications Vancomycin Hydrochloride is an antibiotic used against gram-positive bacterial strains.
References Yao, N., et al.: Biopolymers, 90, 421 (2008); Lai, H., et al.: ACS Appl. Mater. Interfaces, 7, 2046 (2015);Formula:C66H75Cl2N9O24·ClHPurity:90%Color and Shape:NeatMolecular weight:1485.71
