CAS 140401-55-4

1-(3-tert-butylphenyl)methanamine

Description:

1-(3-tert-butylphenyl)methanamine, with the CAS number 140401-55-4, is an organic compound characterized by its amine functional group and a tert-butyl substituent on a phenyl ring. This compound features a methanamine backbone, where a phenyl group is attached to the carbon adjacent to the amine, specifically at the para position relative to the tert-butyl group. The presence of the bulky tert-butyl group contributes to its steric hindrance, which can influence its reactivity and interactions with other molecules. Typically, compounds like this may exhibit moderate solubility in organic solvents and limited solubility in water due to the hydrophobic nature of the tert-butyl group. The amine group can participate in hydrogen bonding, which may affect its boiling point and melting point. Additionally, this compound may have applications in pharmaceuticals or as a building block in organic synthesis, owing to the functional groups present that allow for further chemical modifications. Safety data should be consulted for handling and potential hazards associated with this substance.

Formula: C₁₁H₁₇N

Benzenemethanamine, 3-(1,1-dimethylethyl)-, hydrochloride (1:1)

CAS: 140401-55-4

Formula: C₁₁H₁₈ClN

Purity: 95%

Color and Shape: Solid

Molecular weight: 199.7203

Ref: IN-DA001CCT

3-tert-Butyl-benzylamine hydrochloride

CAS: 140401-55-4

3-tert-Butyl-benzylamine hydrochloride

Purity: 95%

Molecular weight: 199.72g/mol

Ref: 54-OR346151

(3-(Tert-butyl)phenyl)methanamine hydrochloride

CAS: 140401-55-4

Purity: 95+%

Molecular weight: 199.72

Ref: 10-F681269

1-(3-tert-Butylphenyl)methanamine

CAS: 140401-55-4

1-(3-tert-Butylphenyl)methanamine is a potent and selective inhibitor of the enzyme Tryptophan-2,3-dioxygenase (TDO). TDO is an enzyme that catalyzes the conversion of tryptophan to indolepyruvate in the kynurenine pathway. 1-(3-tert-Butylphenyl)methanamine inhibits this conversion, which leads to increased levels of tryptophan in the body. It has been shown to be effective against a range of analytes, including enzymes, with a low nanomolar and nanomolar range. This drug also has an isostere group that allows it to bind at subpockets on the enzyme active site that would not be accessible by other inhibitors.
1-(3-tert-Butylphenyl)methanamine has been shown to inhibit cell proliferation in cell-based assays as well as

Formula: C₁₁H₁₇N

Purity: Min. 95%

Molecular weight: 163.26 g/mol

Ref: 3D-QFA40155