CAS 1404559-17-6

[(2R,4R)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]-3-thiazolidinylmethanone

Description:

The chemical substance with the name "[(2R,4R)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]-3-thiazolidinylmethanone" and CAS number 1404559-17-6 is a complex organic compound characterized by its multi-cyclic structure, which includes a thiazolidine ring, a pyrrolidine moiety, and a piperazine group. This compound features a chiral center, indicating that it exists in specific stereoisomeric forms, which can significantly influence its biological activity and pharmacological properties. The presence of the pyrazole and phenyl groups suggests potential interactions with biological targets, making it of interest in medicinal chemistry. Its molecular structure may confer specific solubility, stability, and reactivity characteristics, which are critical for its application in drug development. Additionally, the compound's synthesis and characterization would typically involve techniques such as NMR spectroscopy, mass spectrometry, and chromatography to confirm its purity and structural integrity. Overall, this compound exemplifies the complexity often found in pharmaceutical agents designed for targeted therapeutic effects.

Formula: C₂₂H₃₀N₆OS

InChI: InChI=1S/C22H30N6OS/c1-17-13-21(28(24-17)18-5-3-2-4-6-18)26-9-7-25(8-10-26)19-14-20(23-15-19)22(29)27-11-12-30-16-27/h2-6,13,19-20,23H,7-12,14-16H2,1H3/t19-,20-/m1/s1

InChI key: InChIKey=WGRQANOPCQRCME-WOJBJXKFSA-N

SMILES: CC=1C=C(N(N1)C2=CC=CC=C2)N3CCN(CC3)[C@@H]4C[C@H](C(=O)N5CCSC5)NC4

Synonyms:

• Methanone, [(2R,4R)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]-3-thiazolidinyl-
• [(2R,4R)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]-3-thiazolidinylmethanone

Teneligliptin (2R,4R)-Isomer

CAS: 1404559-17-6

Formula: C₂₂H₃₀N₆OS

Color and Shape: White To Off-White Solid

Molecular weight: 426.58

Ref: 4Z-T-145004

Teneligliptin R-Isomer

CAS: 1404559-17-6

Formula: C₂₂H₃₀N₆OS

Molecular weight: 426.58

Ref: ST-EA-CP-T16006

(2R,4R)-Teneligliptin-d8

Controlled Product

CAS: 1404559-17-6

Formula: C₂₂H₂₂D₈N₆OS

Color and Shape: Neat

Molecular weight: 434.63

Ref: TR-T018322

(2R,4R)-Teneligliptin

Controlled Product

CAS: 1404559-17-6

Applications (2R,4R)-Teneligliptin is a stereoisomer of Teneligliptin (T018300, HBr); a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used to treat type 2 diabetes. It is eliminated via excretion and has a half-life of 24.2 hours in the human body.
References Goda, M. & Kadowaki, T.: Drugs Today, 49, 615 (2013); Kishimoto, M.: Diabetes Metab. Syndr. Obes., 6, 187 (2012); Yoshida, T., et al.: Bioorg, Med. Chem., 20, 5705 (2012)

Formula: C₂₂H₃₀N₆OS

Color and Shape: Neat

Molecular weight: 426.578

Ref: TR-T018320

(2R,4R)-1-(tert-Butyl Formate)-2-(methyl Formate) Teneligliptin

Controlled Product

CAS: 1404559-17-6

Formula: C₂₅H₃₅N₅O₄

Color and Shape: Neat

Molecular weight: 469.577

Ref: TR-B324330

(2R,4R)-Teneligliptin

CAS: 1404559-17-6

Please enquire for more information about (2R,4R)-Teneligliptin including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₂H₃₀N₆OS

Purity: Min. 95%

Molecular weight: 426.58 g/mol

Ref: 3D-FT171318