CAS 140462-76-6: Olopatadine hydrochloride
Description:Olopatadine hydrochloride is a selective antihistamine primarily used in the treatment of allergic conjunctivitis and allergic rhinitis. It functions as a dual-action agent, exhibiting both antihistaminic and mast cell stabilizing properties, which help alleviate symptoms such as itching, redness, and inflammation. The substance is a white to off-white crystalline powder, soluble in water, and has a molecular formula that reflects its complex structure. Its mechanism of action involves blocking the H1 histamine receptors, thereby preventing the effects of histamine, a key mediator in allergic responses. Olopatadine hydrochloride is typically administered topically in eye drops or intranasally, allowing for localized treatment with minimal systemic absorption. The compound is generally well-tolerated, with a favorable safety profile, although some patients may experience mild side effects such as headache or dry eyes. Its efficacy and safety have made it a common choice in managing allergic conditions, contributing to improved quality of life for individuals suffering from allergies.
Formula:C21H23NO3·ClH
InChI:InChI=1S/C21H23NO3.ClH/c1-22(2)11-5-8-18-17-7-4-3-6-16(17)14-25-20-10-9-15(12-19(18)20)13-21(23)24;/h3-4,6-10,12H,5,11,13-14H2,1-2H3,(H,23,24);1H/b18-8-;
InChI key:InChIKey=HVRLZEKDTUEKQH-NOILCQHBSA-N
SMILES:Cl.O=C(O)CC1=CC=C2OCC=3C=CC=CC3C(=CCCN(C)C)C2=C1
- Synonyms:
- (Z)-11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-acetic acid hydrochloride
- 11-((Z)-3-(Dimethyl-Amino)Propylidene)-6,11-Dihydrodibenz[B,E]Oxepin-2-Acetic Acid
- Allelock
- Allerock
- Alo 4943A
- Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (11Z)-
- Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, hydrochloride (1:1), (11Z)-
- Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, hydrochloride, (11Z)-
- Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, hydrochloride, (Z)-
- Kw 4679
- See more synonyms
- Olopatadine hcl
- Olopax
- Olopine
- Opatanol
- Pataday
- Patadine
- Patanase
- Patanol
- Pazeo
- {(11E)-11-[3-(dimethylamino)propylidene]-6,11-dihydrodibenzo[b,e]oxepin-2-yl}acetic acid
- {(11E)-11-[3-(dimethylamino)propylidene]-6,11-dihydrodibenzo[b,e]oxepin-2-yl}acetic acid hydrochloride (1:1)
- {(11Z)-11-[3-(dimethylamino)propylidene]-6,11-dihydrodibenzo[b,e]oxepin-2-yl}acetic acid
- {(11Z)-11-[3-(dimethylamino)propylidene]-6,11-dihydrodibenzo[b,e]oxepin-2-yl}acetic acid hydrochloride
![Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, hydrochloride (1…](https://static.cymitquimica.com/products/IN/thumb/DA001CHK.jpg)
