CAS 140462-76-6
:Olopatadine hydrochloride
Description:
Olopatadine hydrochloride is a selective antihistamine primarily used in the treatment of allergic conjunctivitis and allergic rhinitis. It functions as a dual-action agent, exhibiting both antihistaminic and mast cell stabilizing properties, which help alleviate symptoms such as itching, redness, and inflammation. The substance is a white to off-white crystalline powder, soluble in water, and has a molecular formula that reflects its complex structure. Its mechanism of action involves blocking the H1 histamine receptors, thereby preventing the effects of histamine, a key mediator in allergic responses. Olopatadine hydrochloride is typically administered topically in eye drops or intranasally, allowing for localized treatment with minimal systemic absorption. The compound is generally well-tolerated, with a favorable safety profile, although some patients may experience mild side effects such as headache or dry eyes. Its efficacy and safety have made it a common choice in managing allergic conditions, contributing to improved quality of life for individuals suffering from allergies.
Formula:C21H23NO3·ClH
InChI:InChI=1S/C21H23NO3.ClH/c1-22(2)11-5-8-18-17-7-4-3-6-16(17)14-25-20-10-9-15(12-19(18)20)13-21(23)24;/h3-4,6-10,12H,5,11,13-14H2,1-2H3,(H,23,24);1H/b18-8-;
InChI key:InChIKey=HVRLZEKDTUEKQH-NOILCQHBSA-N
SMILES:C(\CCN(C)C)=C/1\C=2C(OCC=3C1=CC=CC3)=CC=C(CC(O)=O)C2.Cl
Synonyms:- (Z)-11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-acetic acid hydrochloride
- 11-((Z)-3-(Dimethyl-Amino)Propylidene)-6,11-Dihydrodibenz[B,E]Oxepin-2-Acetic Acid
- Allelock
- Allerock
- Alo 4943A
- Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (11Z)-
- Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, hydrochloride (1:1), (11Z)-
- Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, hydrochloride, (11Z)-
- Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, hydrochloride, (Z)-
- Kw 4679
- Olopatadine hcl
- Olopax
- Olopine
- Opatanol
- Pataday
- Patadine
- Patanase
- Patanol
- Pazeo
- {(11E)-11-[3-(dimethylamino)propylidene]-6,11-dihydrodibenzo[b,e]oxepin-2-yl}acetic acid
- {(11E)-11-[3-(dimethylamino)propylidene]-6,11-dihydrodibenzo[b,e]oxepin-2-yl}acetic acid hydrochloride (1:1)
- {(11Z)-11-[3-(dimethylamino)propylidene]-6,11-dihydrodibenzo[b,e]oxepin-2-yl}acetic acid
- See more synonyms
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Olopatadine Hydrochloride
CAS:Formula:C21H23NO3·HClPurity:>98.0%(HPLC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:373.88Olopatadine Hydrochloride
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFormula:C23H23NO3·HClColor and Shape:White PowderMolecular weight:361.16779Olopatadine hydrochloride
CAS:Olopatadine hydrochloride (ALO4943A) is an antihistamine with mast-cell stabilizing properties used as eye drops in the treatment of ALLERGIC CONJUNCTIVITIS.Formula:C21H24ClNO3Purity:99.62% - 99.64%Color and Shape:White SolidMolecular weight:373.873Olopatadine hydrochloride
CAS:Olopatadine hydrochlorideFormula:C21H24ClNO3Purity:99%Molecular weight:373.87Olopatadine hydrochloride
CAS:Olopatadine hydrochlorideFormula:C21H23NO3·HClPurity:≥98%Molecular weight:373.87Olopatadine hydrochloride
CAS:Formula:C21H23NO3·HClPurity:(HPLC) ≥ 98.0%Color and Shape:White to beige powderMolecular weight:373.87Olopatadine HCl
CAS:Formula:C21H23NO3·HClColor and Shape:Off-White SolidMolecular weight:337.42 36.46Olopatadine Hydrochloride
CAS:Controlled ProductFormula:C21H23NO3·ClHColor and Shape:NeatMolecular weight:373.87(Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride
CAS:Formula:C21H24ClNO3Purity:98%Color and Shape:SolidMolecular weight:373.8732Olopatadine Hydrochloride
CAS:Controlled ProductApplications Dual acting histamine H1-receptor antagonist and mast cell stabilizer. Antiallergic; antihistaminic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kamei, C., et al.: Arzneim.-Forsch., 45, 1005 (1995), Sharif, N.A., et al.: J. Pharmacol. Exp. Ther., 278, 1252 (1996), Abelson, M.B., et al.: Am. J. Ophthalmol., 125, 797 (1998),Formula:C21H23NO3·ClHColor and Shape:NeatMolecular weight:373.87Olopatadine HCl
CAS:(Z)-2-(11-(3-(Dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetic acid hydrochlorideFormula:C21H24ClNO3Purity:98%Molecular weight:373.87Olopatadine HCl
CAS:Ophthalmic anti-allergic agent; prostaglandin D2 and TNFα release inhibitorFormula:C21H24ClNO3Purity:Min. 95%Color and Shape:White PowderMolecular weight:373.87 g/molOlopatadine HCl - Bio-X ™
CAS:Olopatadine is a histamine H1 antagonist that is used to treat allergic conjunctivitis and rhinitis. This drug is also a mast cell stabilizer. Upon binding, Olopatadine blocks the H1 receptor signaling pathway, inhibiting the release of inflammatory mediators, such as tryptase, prostaglandin D2, TNF-alpha, as well as pro-inflammatory cytokines.
Formula:C21H24ClNO3Purity:Min. 95%Color and Shape:PowderMolecular weight:373.87 g/mol
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