CAS 1405-37-4

Capreomycin sulfate

Description:

Capreomycin sulfate is an antibiotic compound primarily used in the treatment of tuberculosis, particularly in cases resistant to standard therapies. It is derived from the bacterium *Streptomyces capreolus* and exhibits a complex structure that includes a cyclic peptide and a fatty acid moiety. Capreomycin functions by inhibiting protein synthesis in bacteria, specifically targeting the ribosomal machinery, which ultimately leads to bacterial cell death. The sulfate form enhances its solubility in water, making it suitable for parenteral administration. Capreomycin is typically administered via injection and is often used in combination with other antitubercular agents to improve efficacy and reduce the risk of resistance. Its use is generally reserved for severe cases due to potential side effects, including nephrotoxicity and ototoxicity. As with many antibiotics, monitoring for adverse reactions and ensuring appropriate dosing is crucial for patient safety and treatment success.

Formula: H₂O₄S·Unspecified

InChI: InChI=1/C25H44N14O7.H2O4S/c1-11-19(41)36-15(9-32-17(40)7-12(27)3-2-5-26)21(43)37-16(10-34-25(30)46)22(44)39-18(14-4-6-31-24(29)38-14)23(45)33-8-13(28)20(42)35-11;1-5(2,3)4/h10-15,18H,2-9,26-28H2,1H3,(H,32,40)(H,33,45)(H,35,42)(H,36,41)(H,37,43)(H,39,44)(H3,29,31,38)(H3,30,34,46);(H2,1,2,3,4)/b16-10-;

SMILES: CC1C(=NC(CN=C(CC(CCCN)N)O)C(=N/C(=C\NC(=N)O)/C(=NC(C2CCNC(=N)N2)C(=NCC(C(=N1)O)N)O)O)O)O.OS(=O)(=O)O

Synonyms:

• 3,6-diamino-N-[[(8Z)-15-amino-11-(2-iminohexahydropyrimidin-4-yl)-2-methyl-3,6,9,12,16-pentaoxo-8-(ureidomethylene)-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]hexanamide
• Capastat sulfate
• Capreomycin Sulfate
• Capreomycin Sulphate
• Capreomycin, sulfate (salt)
• Caprocin
• Sulfuric Acid

Capreomycin sulfate, 90%

CAS: 1405-37-4

Thought to inhibit protein synthesis by inhibiting normal ribosomal functions This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or

Formula: C₂₅H₄₄N₁₄O₈•H₂O₄S

Purity: 90%

Molecular weight: 766.78

Ref: 02-J66684

CAPREOMYCIN SULFATE FOR IDENTIFICATION RS

CAS: 1405-37-4

CAPREOMYCIN SULFATE FOR IDENTIFICATION RS

Ref: 41-ICRS59329

CAPREOMYCIN SULFATE RS

CAS: 1405-37-4

CAPREOMYCIN SULFATE RS

Formula: C₁₂H₁₁NO

Molecular weight: 185.2218

Ref: 41-ICRS58003

Capreomycin Sulfate

CAS: 1405-37-4

Aminoglycoside antibiotics

Formula: H₂O₄S·W₉₉

Color and Shape: White Off-White Powder

Molecular weight: 18309.10954

Ref: 45-1091006

Capreomycin, sulfate (salt)

CAS: 1405-37-4

Formula: C₂₄H₄₄N₁₄O₁₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 752.7578

Ref: IN-DA001CJW

Capreomycin sulfate

CAS: 1405-37-4

Capreomycin sulfate (Capastat sulfate) , a cyclic peptide antibiotic, binds to the 70S ribosomal unit leading to inhibition of protein synthesis.

Formula: C₂₅H₄₆N₁₄O₁₁S

Purity: 98% - 99.54%

Color and Shape: White Powder

Molecular weight: 752.76

Ref: TM-T1441

Capastat sulphate

CAS: 1405-37-4

Formula: C₂₅H₄₄N₁₄O₈·H₂O₄S

Purity: ≥ 90.0% (C25H44N14O8)

Color and Shape: White to off-white powder

Molecular weight: 766.78

Ref: 7W-GA2874

Capreomycin Sulfate

Controlled Product

CAS: 1405-37-4

Applications Capreomycin Sulfate is used in the treatment of MDR-tuberculosis in conjunction with other anti-tuberculosis drugs.
References Garcia-C. et al.: Antimicrob. Agents Chemother., 56, 2612 (2012); Reisfeld, B. et al.: Antimicrob. Agents Chemother., 56, 926 (2012);

Formula: C₁₅H₁₉N₃O₂

Color and Shape: White

Ref: TR-C175675

Capastat sulfate

CAS: 1405-37-4

Capastat sulfate is an antibiotic with action against Mycobacterium tuberculosis by inhibiting protein synthesis and is used for treating tuberculosis.

Formula: C₂₄H₄₂N₁₄O₈·H₂O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 752.76 g/mol

Ref: 3D-AC61430

Capreomycin sulfate

CAS: 1405-37-4

Capreomycin sulfate

Color and Shape: White

Ref: 47-59